Contrast-enhanced MR imaging of breast lesions and effect on treatment
Contrast-enhanced MR imaging of breast lesions and effect on treatment
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DOI：
10.1016/j.ejso.2004.02.003
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发表时间：
2004-06-01
期刊：
影响因子：
3.8
通讯作者：
De Schepper, A
中科院分区：
文献类型：
--
作者：
Schelfout, K;Van Goethem, M;De Schepper, A
目的.目的：探讨术前磁共振成像（MRI）对可疑乳腺病变的局部分期价值及其对治疗方法的影响。204例临床检查（CE）和/或乳房X线摄影（MX）和/或超声（US）显示疑似乳腺病变的连续女性接受了术前对比增强MRI。检测多灶性、多中心性和双侧。乳腺癌的所有三种成像模式进行了评价。与治疗外科医生讨论术前乳腺MRI的结果。在问卷上标记术前MRI后的治疗变化类型（无、额外细针抽吸、空芯活检、开放性活检、广泛切除、乳房切除术），并使用final将其视为“必要”或“不必要”。组织病理学结果作为黄金标准。在170名患者中，诊断出乳腺癌。MRI检测到96%的多灶性疾病和95%的多中心性疾病，而MX分别描述了37%和18%，US分别描述了41%和9%。所有双侧乳腺癌均在MRI上发现; MX和US均检出56%。仅在MRI上发现了更广泛的疾病和意外的多发乳腺癌病灶，这正确改变了30.6%乳腺癌患者的治疗方法。由于MRI高估了恶性病变的数量或大小，共进行了9次不必要的广泛切除和3次不必要的细针穿刺活检。术前乳腺MRI是乳腺癌局部区域分期中常规成像的重要辅助手段，也是一种有用的工具。在治疗计划中。(C)2004爱思唯尔有限公司保留所有权利。
Purpose. To assess the value of local staging with preoperative magnetic resonance imaging (MRI) in patients with suspect breast lesions and the effect on therapeutic approach.Materials and methods. Two hundred and four consecutive women with suspect breast lesions on clinical examination (CE) and/or mammography (MX) and/or ultrasound (US) underwent preoperative contrast-enhanced MRI. Detection of multifocal, multicentric and bilateral. breast cancer by all three imaging modalities was evaluated. Results of preoperative breast MRI were discussed with the treating surgeons. The type of therapeutic change after preoperative MRI was marked on a questionnaire (none, additional fine needle aspiration, core biopsy, open biopsy, wider excision, mastectomy) and considered 'necessary' or 'unnecessary' using final. histopathological. results as gold standard.Results. In 170 patients, breast cancer was diagnosed. MRI detected 96% of multifocat disease and 95% of multicentric disease, whereas MX depicted 37 and 18%, and US 41 and 9% of them, respectively. All bilateral breast cancers were seen on MRI; both MX and US detected 56%. Findings of more extensive disease and unsuspected multiple breast cancer foci identified on MRI only, changed the therapeutic approach correctly in 30.6% of breast cancer patients. Nine unnecessary wider excisions and three unnecessary FNA/core biopsies were performed because MRI overestimated the number or size of malignant lesions.Conclusion. Preoperative breast MRI is an important adjunct to conventional imaging in the loco-regional staging of breast cancer and a useful tool. in treatment planning. (C) 2004 Elsevier Ltd. All rights reserved.