CORONARY SPASM WITH VENTRICULAR-FIBRILLATION DURING THYROTOXICOSIS - RESPONSE TO ATTAINING EUTHYROID STATE
CORONARY SPASM WITH VENTRICULAR-FIBRILLATION DURING THYROTOXICOSIS - RESPONSE TO ATTAINING EUTHYROID STATE
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DOI：
10.1016/s0002-9149(79)80023-5
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发表时间：
1979-01-01
影响因子：
2.8
通讯作者：
ACHUFF, SC
中科院分区：
文献类型：
--
作者：
WEI, JY;GENECIN, A;ACHUFF, SC
虽然冠状动脉正常的甲状腺功能亢进患者也可能发生心肌缺血，但其机制尚不清楚。本文报告一位甲状腺机能亢进症的女性，在心肌缺血时发生心室颤动。通过连续动态心电图记录该事件。随后的血管造影显示冠状动脉解剖正常，右冠状动脉痉挛，舌下含服一片硝酸甘油后消失。甲状腺功能正常后，心绞痛、心肌缺血的心电图证据、室性心律失常和患者对硝酸甘油的需求消失。这些发现提示甲亢患者冠状动脉痉挛可能与心肌缺血和心律失常有关。
Although myocardial ischemia may occur in thyrotoxic patients with normal coronary arteries, the mechanism remains unclear. This report describes a woman with hyperthyroidism who had ventricular fibrillation during an episode of myocardial ischemia. The event was documented with continuous ambulatory electrocardiography. Subsequent angiography revealed normal coronary anatomy with spasm of the right coronary artery that disappeared after ingestion of one sublingual nitroglycerin tablet. The angina, electrocardiographic evidence of myocardial ischemia, ventricular arrhythmias and the patient's need for nitroglycerin were eliminated after she became euthyroid. These findings suggest that coronary spasm may be associated with myocardial ischemia and arrhythmias in a hyperthyroid patient.