CONNECTIONS OF AREAS 3B AND 1 OF THE PARIETAL SOMATOSENSORY STRIP WITH THE VENTROPOSTERIOR NUCLEUS IN THE OWL MONKEY (AOTUS-TRIVIRGATUS)
CONNECTIONS OF AREAS 3B AND 1 OF THE PARIETAL SOMATOSENSORY STRIP WITH THE VENTROPOSTERIOR NUCLEUS IN THE OWL MONKEY (AOTUS-TRIVIRGATUS)
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DOI：
10.1002/cne.901850209
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发表时间：
1979-01-01
影响因子：
2.5
通讯作者：
KAAS, JH
中科院分区：
文献类型：
--
作者：
LIN, CS;MERZENICH, MM;KAAS, JH
在微电极标测实验中，对猫头猴的体感皮层3b区(SI本身)和I区(皮后区)的电生理定位部位进行了广泛的研究，并对这些部位进行了解剖示踪剂的注射。这些标测实验表明，区域3b和1都包含身体表面的完整和独立的表示(Merzenich等人，‘’78)。限制将逆行示踪剂辣根过氧化物酶(HRP)注射到腹后核(VP)内的3b区或1区标记神经元。在两种表征中，VP标记带的位置随注射部位的位置不同而不同，在两种表征中，在相应的身体部位注射时，VP的标记区域是重叠的。投射到手部和足部皮质表示的神经元位于结构上被识别的亚核。因为注射到3b区或1区，在VP的适当区域标记了超过一半的神经元，所以VP内的一些神经元似乎投射到两个皮质代表。注射HRP和顺行示踪剂~3H-Pro表明，VP神经元与3b区和1区相互联系。
Anatomical tracers were injected into electrophysiologically defined sites in somatosensory cortical Area 3b (SI proper) and Area I (posterior cutaneous field) of owl monkeys after these cortical subdivisions had been extensively explored in microelectrode mapping experiments. These mapping experiments revealed that both Areas 3b and 1 contain complete and separate representations of the body surface (Merzenich et al., ''78). Restricted injections of the retrograde tracer, horseradish peroxidase (HRP), into either Area 3b or Area 1 labeled neurons within a band of cells in the ventroposterior nucleus (VP). The location of the labeled band in VP varied with the location of the injection site in both representations, and the labeled region of VP was overlapping for injections in corresponding body parts in the 2 representations. Neurons projecting to the hand and foot cortical representations were in architectonically identified subnuclei. Because injections into either Area 3b or Area 1 labeled over half of the neurons in the appropriate regions of VP, it appears that some neurons in VP project to both cortical representations. Injections of HRP combined with the anterograde tracer, 3H-proline, indicate that VP neurons are reciprocally interconnected with both Areas 3b and 1.