Radiation-induced meningioma
Radiation-induced meningioma
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DOI：
10.3171/foc/2008/24/5/e7
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发表时间：
2008-05-01
影响因子：
4.1
通讯作者：
Spektor, Sergey
中科院分区：
文献类型：
--
作者：
Umansky, Felix;Shoshan, Yigal;Spektor, Sergey
目前已知，辐射对神经组织的长期或延迟副作用包括诱导新的中枢神经系统肿瘤。然而，在20世纪上半叶，人们普遍认为人类神经组织对电离辐射的致癌和其他不良影响具有相对的抵抗力。因此，在诊断检查和治疗过程中暴露于相对高剂量的x射线是很常见的。在本文中，作者回顾了有关辐射诱发脑膜瘤（RIMs）的文献。重点是由于儿童时期治疗原发性脑瘤或头癣、接受牙科x光照射以及在广岛和长崎遭受原子弹爆炸而造成的脑膜瘤。本文介绍了高剂量和低剂量辐射下rim的发病率和自然史，包括潜伏期、多样性、组织病理学特征和复发率。作者回顾了rim患者的典型表现，并根据他们治疗这些病变的临床经验，与散发性脑膜瘤相比，讨论了这些肿瘤手术治疗的独特方面。
The long-term or delayed side effects of irradiation on neural tissue are now known to include the induction of new central nervous system neoplasms. However, during the first half of the 20th century, human neural tissue was generally considered relatively resistant to the carcinogenic and other ill effects of ionizing radiation. As a result, exposure to relatively high doses of x-rays from diagnostic examinations and therapeutic treatment was common.In the present article the authors review the literature relating to radiation-induced meningiomas ( RIMs). Emphasis is placed on meningiomas resulting from childhood treatment for primary brain tumor or tinea capitis, exposure to dental x-rays, and exposure to atomic explosions in Hiroshima and Nagasaki. The incidence and natural history of RIMs following exposure to high- and low-dose radiation is presented, including latency, multiplicity, histopathological features, and recurrence rates. The authors review the typical presentation of patients with RIMs and discuss unique aspects of the surgical management of these tumors compared with sporadic meningioma, based on their clinical experience in treating these lesions.