Masticatory rhythm in intracellular potential of trigeminal motoneurons induced by stimulation of orbital cortex and amygdala in cats
Masticatory rhythm in intracellular potential of trigeminal motoneurons induced by stimulation of orbital cortex and amygdala in cats
复制标题
刺激猫眶皮层和杏仁核诱导的三叉神经元细胞内电位的咀嚼节律
DOI：
10.1016/0006-8993(78)90738-2
复制
发表时间：
1978
期刊：
影响因子：
2.9
通讯作者：
Yoshihiro Kubo
中科院分区：
文献类型：
--
作者：
Yasuhisa Nakamura;Yoshihiro Kubo
Fig. 1.中枢诱导的咀嚼节律在下颌关闭运动神经元。A和C：从右咬肌（上）和右前二腹肌（中）记录的EMG和通过重复刺激左眶回（40次/秒，持续时间0.3毫秒，6V）（A）和左外侧杏仁核（40次/秒，0.3毫秒，6V）（C）诱导的下颌运动（下）。C中带箭头的条表示完全咬合（a和B）和强直性紧咬（c）的时期。B和D：刺激左侧眶回（B）和外侧杏仁核（D）诱发的节律电位的左侧靠近下颌的运动神经元的细胞内记录。B和D分别在动物制动后通过施加与A和C中相同的刺激来记录。B和D中的虚线表示静息细胞内电位水平（~ 56 mV）。图B和D所示的近颌运动神经元由刺激左侧三叉神经中脑核诱发的单突触EPSP和锋电位确定（1/sec，0.1 msec，4 V，2 msec间隔的两次电击）和左下牙槽神经刺激诱发的短潜伏期IPSP（1/sec，0.03 msec，7 V），分别如E和F所示，其中记录由5个叠加道组成。另一个靠近下颌的运动神经元对刺激静止猫左眶回（40/sec，0.3 msec，8 V）的GK细胞内反应。GK中的虚线表示静息电位水平（-53 mV）。H和I：以更快的扫描和更高的增益记录G中由上水平条标记的部分。H和I中的向上箭头表示第二超极化电位的逐渐增加。J和K：以更快的扫描和更高的增益叠加连续记录，这些记录由G中较低的水平条标记。在J中，细胞内电位水平从静息水平逐渐沿去极化方向移动，如向上箭头所示，然后沿超极化方向移动，如向下箭头所示;在K中，细胞内电位水平沿去极化方向从底部向顶部移动，如向上箭头所示。J下方的向上箭头表示第二超极化电位峰值的大致时间。D和HK中的尖峰电位被截断。AD和G中的向上箭头和G中的向下箭头分别指示重复刺激的开始和停止。H和I中的点表示刺激施加的时间。400/~ V和1 mV的电压校准分别适用于A和C中的顶部和中间记录。A和C的底部记录中的上（CL）和下（OP）水平条分别表示下颌骨的闭合和最大张开位置。B和F中的时基分别适用于AD、E和F; B和F中的电压校准分别适用于B、D和E、F。I和K中的时基和电压校准分别适用于H，I和J，K。
Fig. 1. Centrally induced masticatory rhythm in jaw-closer motoneurons. AD were obtained from the same cat. A and C: EMG recorded from right masseteric (top) and right anterior digastric muscles (middle) and jaw movement (bottom) induced by repetitive stimulation of left orbital gyrus (40/sec, 0.3 msec in duration, 6 V)(A) and of left lateral amygdaloid nucleus (40/see, 0.3 msec, 6 V)(C). Bars with arrows in C indicate periods of complete biting (a and b) and tonic clenching (c). B and D: intracellular records from a left jaw-closer motoneuron of rhythmical potential evoked by stimulation of orbital gyrus (B) and lateral amygdaloid nucleus on the left side (D). B and D were recorded after immobilization of the animal by application of the same stimulation as in A and C, respectively. Broken lines in B and D represent resting intracellular potential level (--56 mV). The jaw-closer motoneuron shown in B and D was identified by monosynaptic EPSPs and spike potentials evoked by stimulation of left trigeminal mesencephalic nucleus (1/sec, 0.1 msec, 4 V, two shocks in 2 msec interval) and by short-latency IPSPs evoked by left inferior alveolar nerve stimulation (1/sec, 0.03 msec, 7 V), as shown respectively in E and F, in which records consist of 5 superimposed traces. GK-intracellular responses of another jaw-closer motoneuron to stimulation of left orbital gyrus (40/sec, 0.3 msec, 8 V) in an immobilized cat. Broken lines in GK show resting potential level (--53 mV). H and I: records in a faster sweep and a higher gain of parts marked by upper horizontal bars in G. Upward arrows in H and I indicate gradual increase in the second hyperpolarizing potential. J and K: superimposed successive records in a still faster sweep and a higher gain of parts marked by lower horizontal bars in G. In J, intracellular potential level shifted gradually in depolarizing direction from resting level as indicated by upward arrow and then in hyperpolarizing direction as shown by downward arrow; in K, intracellular potential level shifted in depolarizing direction from bottom to top traces as shown by upward arrow. Upward arrow below J indicates approximate time of peak of second hyperpolarizing potential. Spike potentials in D and HK are truncated. Upward arrows in AD and G and downward arrow in G indicate onset and cessation of repetitive stimulation, respectively. Dots in H and I indicate time of stimulus application. Voltage calibrations of 400/~ V and 1 mV in A apply respectively to top and middle records in A and C. Upper (CL) and lower (OP) horizontal bars in bottom records of A and C represent respectively closed and maximal opening position of the mandible. Time bases in B and F apply respectively to AD and E and F; voltage calibrations in B and F apply respectively to B, D and E, F. Time bases and voltage calibrations in I and K apply respectively to H, I and J, K.