THE WISCONSIN EPIDEMIOLOGIC-STUDY OF DIABETIC-RETINOPATHY .2. PREVALENCE AND RISK OF DIABETIC-RETINOPATHY WHEN AGE AT DIAGNOSIS IS LESS THAN 30 YEARS
THE WISCONSIN EPIDEMIOLOGIC-STUDY OF DIABETIC-RETINOPATHY .2. PREVALENCE AND RISK OF DIABETIC-RETINOPATHY WHEN AGE AT DIAGNOSIS IS LESS THAN 30 YEARS
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DOI：
10.1001/archopht.1984.01040030398010
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发表时间：
1984-01-01
影响因子：
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通讯作者：
DEMETS, DL
中科院分区：
文献类型：
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作者：
KLEIN, R;KLEIN, BEK;DEMETS, DL
在威斯康星州南部进行的一项基于人群的研究中，使用标准方案对996名服用胰岛素的初发糖尿病患者进行了检查，以确定糖尿病视网膜病变的患病率和严重程度以及相关的风险变量。糖尿病病程< 5年和15年及以上的糖尿病患者视网膜病变的患病率分别为17%~ 97.5%。糖尿病病程< 10年及≥ 10年的患者中，视网膜病变的发生率为1.2%-67%。35岁，分别。糖尿病患者10年的持续时间，考克斯回归模型将视网膜病变的严重程度与较长的持续时间、检查时年龄较大和较高的糖化血红蛋白水平相关。糖尿病10年后，视网膜病变的严重程度与病程较长、糖化血红蛋白水平高、蛋白尿、舒张压升高和男性有关。
In a population-based study in southern Wisconsin, 996 insulin-taking, younger-onset diabetic persons were examined using standard protocols to determine the prevalence and severity of diabetic retinopathy and associated risk variables. The prevalence of diabetic retinopathy varied from 17% to 97.5% in persons with diabetes for < 5 yr and 15 or more yr, respectively. Proliferative retinopathy varied from 1.2% to 67% in persons with diabetes for < 10 yr and .gtoreq. 35 yr, respectively. For persons with diabetes of .ltoreq. 10 yr duration, the Cox regression model relates the severity of retinopathy to longer duration, older age at examination and higher levels of glycosylated Hb. After 10 yr of diabetes, severity of retinopathy was related to longer duration, high levels of glycosylated Hb, presence of proteinuria, higher diastolic BP [blood pressure] and male sex.