Signal-to-noise ratio enhancement of intermolecular double-quantum coherence MR spectroscopy in inhomogeneous fields with phased array coils on a 3 Tesla whole-body scanner.
Signal-to-noise ratio enhancement of intermolecular double-quantum coherence MR spectroscopy in inhomogeneous fields with phased array coils on a 3 Tesla whole-body scanner.
复制标题
在 3 特斯拉全身扫描仪上使用相控阵线圈增强非均匀场中分子间双量子相干磁共振波谱的信噪比。
DOI：
10.1002/jmri.22434
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发表时间：
2011
期刊：
影响因子：
--
通讯作者：
Zhong,Jianhui
中科院分区：
文献类型：
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作者：
Lin,Yanqin;Chen,Zhong;Zhong,Jianhui
目的提高3特斯拉(T)全身扫描仪分子间双量子相干(IDQC)MRS信号的信噪比。材料与方法采用32通道相控阵线圈在大场不均匀条件下采集MRS模体的iDQC信号。使用多通道非参数奇异值分解算法在时间域中将从阵列单元获得的单个频谱组合在一起。结果相对于圆极化磁头线圈获得的信噪比增益范围为1.63~2.10，主要取决于相控阵线圈表面与采集体素之间的相对位置。结论在3T全身扫描仪上，利用相控阵线圈增强非均匀场中iDQC MRS的信噪比是可行的。这可以促进高分辨率活体光谱的iDQC应用，在存在场不均匀的情况下，用于潜在的人类疾病诊断。J·马根。雷森。成像2011；33：698-703。©2011 Wiley-Liss，Inc.
PurposeTo improve signal‐to‐noise ratio (SNR) of intermolecular double‐quantum coherence (iDQC) MRS on a 3 Tesla (T) whole‐body scanner.Materials and MethodsA 32‐channel phased array coil was used to acquire iDQC signal of a MRS phantom in the presence of large field inhomogeneity. The obtained individual spectra from the array elements were combined together in the time domain using a multichannel nonparametric singular value decomposition algorithm. The results were compared quantitatively with those acquired with a circularly polarized (CP) head coil.ResultsThe achieved gain in SNR ranges from 1.63 to 2.10 relative to the CP coil, mainly depending on the relative position between the surface of the phased array coil and the voxel of acquisition.ConclusionSNR enhancement of iDQC MRS in inhomogeneous fields on a 3T whole‐body scanner is feasible with phased array coils. This can facilitate iDQC applications of high‐resolution in vivo spectroscopy in the presence of field inhomogeneity for potential disease diagnosis in humans. J. Magn. Reson. Imaging 2011;33:698–703. © 2011 Wiley‐Liss, Inc.