EPIDEMIOLOGIC DIFFERENCES AMONG SEROTYPES OF CRYPTOCOCCUS-NEOFORMANS

EPIDEMIOLOGIC DIFFERENCES AMONG SEROTYPES OF CRYPTOCOCCUS-NEOFORMANS
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DOI:
10.1093/oxfordjournals.aje.a112423
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发表时间:
1977-01-01
影响因子:
5
通讯作者:
HOWARD, DH
HOWARD, DH
中科院分区:
医学2区
文献类型:
--
作者:
BENNETT, JE;KWONCHUNG, KJ;HOWARD, DH

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在美国,最常见的新形梭菌血清型为a型。在272个感染分离株中有203个血清型,在89个环境分离株中有85个血清型。血清型B或C分离株是罕见的感染原因,除了在南加州,而且根本没有从环境源中分离出来。在南加州,67株土壤和鸽子粪便分离株中没有血清型B和C,考虑到49株感染分离株中有25株为血清型B或C,这是令人震惊的。自然界中存在血清型B和C的地点目前尚不清楚,但与血清型A和D不同。在这些国家的24株分离株中,21株为血清D型。
In the USA, the most prevalent serotype of the fungus C. neoformans was serotype A. This serotype constituted 203 of 272 isolates from infections and 85 of 89 isolates from the environment. Serotype B or C isolates were infrequent causes of infection, except in southern California, and were not isolated at all from environmental sources. In southern California, the absence of serotypes B and C in 67 soil and pigeon dropping isolates was striking, considering that 25 of 49 isolates from infections were serotypes B or C. The site in nature where serotypes B and C exist is currently unknown but differs from that of serotypes A and D. Serotype D may be unusually prevalent in environmental and patient isolates from Denmark and Italy. Of 24 isolates from those countries, 21 were serotype D.