Evolutionary history of the Coccolithoviridae
Evolutionary history of the Coccolithoviridae
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DOI：
10.1093/molbev/msj010
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发表时间：
2006-01-01
影响因子：
10.7
通讯作者：
Wilson, WH
中科院分区：
文献类型：
--
作者：
Allen, MJ;Schroeder, DC;Wilson, WH
我们最近确定了球石病毒科菌株Emiliania huxleyi病毒86（EhV-86）的基因组序列，EhV-86是一种来自藻DNA病毒科的巨型双链DNA（dsDNA）藻类病毒，感染海洋球石藻E。huxleyi。在这里，我们确定EhV-86和其他大型dsDNA病毒之间的系统发育关系。在EhV-86基因组中鉴定了25个核质大dsDNA病毒基因组共有的核心基因;来自这些基因中的8个的序列被用于创建系统发育树，其中EhV-86与藻DNA病毒科的其他两个成员牢固地放置在一起。我们还鉴定了EhV-86基因组的一个100 kb区域，该区域似乎从未知来源转移到该基因组中。此外，六个RNA聚合酶亚基（在藻DNA病毒科中是独特的）的存在表明了这种有趣的病毒的独特进化历史和独特的生活方式。
We recently determined the genome sequence of the Coccolithoviridae strain Emiliania huxleyi virus 86 (EhV-86), a giant double-stranded DNA (dsDNA) algal virus from the family Phycodnaviridae that infects the marine coccolithophorid E. huxleyi. Here, we determine the phylogenetic relationship between EhV-86 and other large dsDNA viruses. Twenty-five core genes common to nuclear-cytoplasmic large dsDNA virus genomes were identified in the EhV-86 genome; sequence from eight of these genes were used to create a phylogenetic tree in which EhV-86 was placed firmly with the two other members of the Phycodnaviridae. We have also identified a 100-kb region of the EhV-86 genome which appears to have transferred into this genome from an unknown source. Furthermore, the presence of six RNA polymerase subunits (unique among the Phycodnaviridae) suggests both a unique evolutionary history and a unique lifestyle for this intriguing virus.