The association between dietary patterns with type 2 diabetes mellitus and pre-diabetes in the Henan rural cohort study
The association between dietary patterns with type 2 diabetes mellitus and pre-diabetes in the Henan rural cohort study
复制标题
河南农村队列研究膳食模式与2型糖尿病及糖尿病前期的关系
DOI：
10.1017/s1368980021000227
复制
发表时间：
2021
影响因子：
3.2
通讯作者：
Li Xing
中科院分区：
文献类型：
--
作者：
Xue Yuan;Liu Chang;Wang Bingya;Mao Zhenxing;Yu Songcheng;Wang Yan;Zhang Dongdong;Wang Chongjian;Li Wenjie;Li Xing
目的探讨河南省农村地区成人2型糖尿病（T2 DM）及糖尿病前期的危险性与膳食结构的关系。采用主成分分析法确定膳食结构，采用多元Logistic回归分析和限制性三次样条回归模型分析膳食结构与糖尿病前期和2型糖尿病的关系。中国.青少年共有38 779名18-结果河南省农村人群糖尿病前期患病率为6.8%，T2 DM患病率为9.4%。本研究共评估了三种饮食模式。饮食模式I，红肉和白色肉摄入量高;饮食模式II，谷物、坚果、牛奶和鸡蛋摄入量高;饮食模式III，蔬菜、主食和水果摄入量高。模式III的最高五分位数（Q5）可以降低32.7%的糖尿病前期风险。模式II的Q5可降低2型糖尿病风险15.5%，呈U型剂量-反应关系，模式III的Q5与2型糖尿病风险降低显著相关（OR：0.582，95%CI（0.497，0.682））。虽然“谷物-坚果-鸡蛋”的摄入量较高可能与T2 DM风险降低有关，但应避免过量摄入。本研究可为糖尿病的饮食预防提供参考。
ObjectiveWe aimed to investigate whether dietary patterns were associated with the risk of type 2 diabetes mellitus (T2DM) or pre-diabetes in adults of rural area in Henan.DesignCross-sectional study. Principal component analysis was used to identify dietary patterns, while multivariate logistic regression analysis and restricted cubic spline regression models were used to analyse the association between dietary patterns and both pre-diabetes and T2DM.SettingRural area of Henan province, China.ParticipantsA total of 38 779 adults aged 18–79 years were recruited from the Henan rural cohort study as the subjects.ResultsThe prevalence of pre-diabetes and T2DM in rural Henan was 6·8 % and 9·4 %, respectively. A total of three dietary patterns were assessed in the present study. Dietary pattern I with a high intake of red meat and white meat; dietary pattern II with a high intake of grains, nuts, milk and eggs and dietary pattern III with a high intake of vegetables, staple food and fruits. The highest quintile (Q5) of pattern III could reduce 32·7 % risk of pre-diabetes. The Q5 of pattern II showed a 15·5 % decreased risk of T2DM, in a U-shaped dose–response manner; meanwhile, the Q5 of pattern III was significantly associated with reduced risks of T2DM (OR: 0·582, 95 % CI (0·497, 0·682)).ConclusionsPattern III is beneficial for reducing risk of pre-diabetes or T2DM. Though a higher consumption of ‘grains-nuts-egg’ may associate with a reduced risk of T2DM, excessive intakes should be avoided. This study may provide a reference for the prevention of diabetes on dietary precautions.