Antimicrobial Prescribing in Dogs and Cats in Australia: Results of the Australasian Infectious Disease Advisory Panel Survey
Antimicrobial Prescribing in Dogs and Cats in Australia: Results of the Australasian Infectious Disease Advisory Panel Survey
复制标题
DOI：
10.1111/jvim.14733
复制
发表时间：
2017-07-01
影响因子：
2.6
通讯作者：
Stevenson, M.
中科院分区：
文献类型：
--
作者：
Hardefeldt, L. Y.;Holloway, S.;Stevenson, M.
背景：伴侣动物中抗菌药物使用的研究有限。随着人们越来越认识到需要改善抗菌药物的管理，迫切需要更详细地了解抗菌药物的使用模式，在这一sector.Objectives：调查抗菌药物的使用在狗和猫的医疗和手术条件下，澳大利亚veterinarias.Methods：一个横断面研究进行了4个月以上，在2011年。受访者被问及他们对犬和猫疾病经验性治疗的抗菌剂选择、治疗持续时间以及基于培养和药敏试验的选择，常见条件被框定为病例情景：11例内科，2例外科，8例皮肤科。在完成调查的1，029名澳大利亚兽医专业人员中，共有892人符合选择标准。经验性抗菌治疗在急性疾病中（76%）比慢性疾病（24%）更常见。总体而言，最常见的抗菌药物类别为增强氨基青霉素类（36%）、氟喹诺酮类（15%）、第一代和第二代头孢菌素类（14%）和四环素类（11%）。与犬（2%）相比，猫（16%）更常使用第三代头孢菌素。澳大利亚传染病咨询小组（AIDAP）指南（随后产生的）是可变的，范围从0到69%之间的条件。结论和临床意义：澳大利亚兽医从业者对抗菌剂的选择总体上是适当的，除了在犬中经验性使用氟喹诺酮类药物外，特别是用于外耳炎和猫的第三代头孢菌素。未来的调查将确定2013年AIDAP治疗指南的引入是否影响了处方习惯。
Background: Investigations of antimicrobial use in companion animals are limited. With the growing recognition of the need for improved antimicrobial stewardship, there is urgent need for more detailed understanding of the patterns of antimicrobial use in this sector.Objectives: To investigate antimicrobial use for medical and surgical conditions in dogs and cats by Australian veterinarians.Methods: A cross-sectional study was performed over 4 months in 2011. Respondents were asked about their choices of antimicrobials for empirical therapy of diseases in dogs and cats, duration of therapy, and selection based on culture and susceptibility testing, for common conditions framed as case scenarios: 11 medical, 2 surgical, and 8 dermatological.Results: A total of 892 of the 1,029 members of the Australian veterinary profession that completed the survey satisfied the selection criteria. Empirical antimicrobial therapy was more common for acute conditions (76%) than chronic conditions (24%). Overall, the most common antimicrobial classes were potentiated aminopenicillins (36%), fluoroquinolones (15%), first- and second-generation cephalosporins (14%), and tetracyclines (11%). Third-generation cephalosporins were more frequently used in cats (16%) compared to dogs (2%). Agreement with Australasian Infectious Disease Advisory Panel (AIDAP) guidelines (generated subsequently) was variable ranging from 0 to 69% between conditions.Conclusions and Clinical Importance: Choice of antimicrobials by Australian veterinary practitioners was generally appropriate, with relatively low use of drugs of high importance, except for the empirical use of fluoroquinolones in dogs, particularly for otitis externa and 3rd-generation cephalosporins in cats. Future surveys will determine whether introduction of the 2013 AIDAP therapeutic guidelines has influenced prescribing habits.