Initial assessment of tumor tracking with a gimbaled linac system in clinical circumstances: A patient simulation study
Initial assessment of tumor tracking with a gimbaled linac system in clinical circumstances: A patient simulation study
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DOI：
10.1016/j.radonc.2012.12.015
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发表时间：
2013-02-01
影响因子：
5.7
通讯作者：
De Ridder, Mark
中科院分区：
文献类型：
--
作者：
Depuydt, Tom;Poels, Kenneth;De Ridder, Mark
目的：为了初步评估Vero动态跟踪工作流程在临床环境中的应用情况，并量化跟踪系统的性能，对5名肺和肝脏患者进行了模拟研究。方法和材料：肿瘤跟踪治疗的准备步骤是基于植入肿瘤的基准标记物，允许使用万向架直线加速器跟踪肿瘤并监测X射线采集，但不激活6 MV射束。结果：患者进入治疗室至第一个治疗场的平均时间约为9min。建立相关模型的时间为3.2min。在平移/倾斜方向和3.08 mm的2D范围内，观察到跟踪误差分别为0.55和0.95 mm(1 Sigma)。确定的皮肤剂量为0.08 mGY/像，源-皮肤距离为900 mm，千伏照射量为1 mAs。在1赫兹监测下，平均观察到1.8mGY/min千伏皮肤剂量。结论：Vero跟踪方案功能齐全，性能可与其他实时跟踪系统相媲美。(C)2013爱思唯尔爱尔兰有限公司。保留所有权利。放射治疗与肿瘤学106(2013)236-240
Purpose: To have an initial assessment of the Vero Dynamic Tracking workflow in clinical circumstances and quantify the performance of the tracking system, a simulation study was set up on 5 lung and liver patients.Methods and materials: The preparatory steps of a tumor tracking treatment, based on fiducial markers implanted in the tumor, were executed allowing pursuit of the tumor with the gimbaled linac and monitoring X-rays acquisition, however, without activating the 6 MV beam. Data were acquired on workflow time-efficiency, tracking accuracy and imaging exposure.Results: The average time between the patient entering the treatment room and the first treatment field was about 9 min. The time for building the correlation model was 3.2 min. Tracking errors of 0.55 and 0.95 mm (1 sigma) were observed in PAN/TILT direction and a 2D range of 3.08 mm. A skin dose was determined of 0.08 mGy/image, with a source-to-skin distance of 900 mm and kV exposure of 1 mAs. On average 1.8 mGy/min kV skin dose was observed for 1 Hz monitoring.Conclusion: The Vero tracking solution proved to be fully functional and showed performance comparable with other real-time tracking systems. (C) 2013 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 106 (2013) 236-240