A comparison of proximity and land use regression traffic exposure models and wheezing in infants.
A comparison of proximity and land use regression traffic exposure models and wheezing in infants.
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DOI：
10.1289/ehp.9480
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发表时间：
2007-02
影响因子：
10.4
通讯作者：
Grinshpun, Sergey A
中科院分区：
文献类型：
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作者：
Ryan, Patrick H;Lemasters, Grace K;Biswas, Pratim;Levin, Linda;Hu, Shaohua;Lindsey, Mark;Bernstein, David I;Lockey, James;Villareal, Manuel;Khurana Hershey, Gurjit K;Grinshpun, Sergey A
我们之前报道过婴儿喘息与居住距离走走停停的公共汽车和卡车交通< 100米之间的关联。然而，使用接近模型可能导致暴露错误分类。利用土地利用回归（LUR）模型得到的卡车和公共汽车交通暴露的结果与接近模型得到的结果进行了比较。从LUR模型得出的估计值与婴儿喘息有关。我们从空气动力学直径< 2.5 μm的颗粒物的环境监测结果中得出了柴油燃烧的标志——交通源元素碳（ECAT）。我们建立了一个以ECAT为结果变量的多元回归模型。模型中包含的变量包括主要道路的位置、公共汽车路线、卡车交通数量和海拔。应用模型参数估计来估计婴儿家中的个体ECAT水平。监测站ECAT估测值在0.20 ~ 1.02 μg/m3之间。在婴儿家中应用了具有决定系数（R2）为0.75的LUR暴露模型。先前被归类为未暴露、暴露于走走停停的交通或暴露于移动交通的婴儿的ECAT平均环境暴露（±SD）分别为0.32±0.06、0.42±0.14和0.49±0.14 μg/m3。0.30 ~ 0.90 μg/m3的ECAT水平与婴儿喘息显著相关。LUR模型为所有婴儿家庭单独导出了一系列ECAT，这可能会减少因接近模型而产生的暴露错误分类。
We previously reported an association between infant wheezing and residence < 100 m from stop-and-go bus and truck traffic. The use of a proximity model, however, may lead to exposure misclassification. Results obtained from a land use regression (LUR) model of exposure to truck and bus traffic are compared with those obtained with a proximity model. The estimates derived from the LUR model were then related to infant wheezing. We derived a marker of diesel combustion—elemental carbon attributable to traffic sources (ECAT)—from ambient monitoring results of particulate matter with aerodynamic diameter < 2.5 μm. We developed a multiple regression model with ECAT as the outcome variable. Variables included in the model were locations of major roads, bus routes, truck traffic count, and elevation. Model parameter estimates were applied to estimate individual ECAT levels at infants’ homes. The levels of estimated ECAT at the monitoring stations ranged from 0.20 to 1.02 μg/m3. A LUR model of exposure with a coefficient of determination (R2) of 0.75 was applied to infants’ homes. The mean (± SD) ambient exposure of ECAT for infants previously categorized as unexposed, exposed to stop-and-go traffic, or exposed to moving traffic was 0.32 ± 0.06, 0.42 ± 0.14, and 0.49 ± 0.14 μg/m3, respectively. Levels of ECAT from 0.30 to 0.90 μg/m3 were significantly associated with infant wheezing. The LUR model resulted in a range of ECAT individually derived for all infants’ homes that may reduce the exposure misclassification that can arise from a proximity model.