THE RELATIONSHIP OF MACULAR MICROCIRCULATION TO VISUAL-ACUITY IN DIABETIC-PATIENTS
THE RELATIONSHIP OF MACULAR MICROCIRCULATION TO VISUAL-ACUITY IN DIABETIC-PATIENTS
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DOI：
10.1001/archopht.1995.01100050078034
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发表时间：
1995-05-01
影响因子：
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通讯作者：
REIM, M
中科院分区：
文献类型：
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作者：
AREND, O;WOLF, S;REIM, M
目的：探讨无明显黄斑水肿的糖尿病性黄斑病变的裂孔周围微循环及其与视力的关系。设计：前瞻性分析。环境：教学医院。患者：15例视力受损20/50或更差的患者，视力未受影响的糖尿病对照人群（年龄、性别、视网膜病变分期相匹配）和52例健康对照。干预措施：研究包括视频荧光素血管造影，图像分析和血红蛋白A（1c）测量。主要观察指标：黄斑毛细血管血流速度、毛细血管密度（凹周毛细血管间面积）、中央凹无血管区。结果：两组患者毛细血管血流速度均明显降低(P
Objective: To assess the perifoveal microcirculation in diabetic maculopathy without clinically significant macular edema and its relationship to visual acuity.Design: Prospective analysis.Setting: A teaching hospital.Patients: Fifteen patients with impaired visual acuity of 20/50 or worse, a diabetic control population with unaffected visual acuity (matched age, gender, retinopathy stage), and 52 healthy controls were enrolled.Interventions: Study consisted of video-fluorescein angiography with image analyses and hemoglobin A(1c) measurements.Main Outcome Measures: Macular capillary blood velocity, capillary density (perifoveal intercapillary area), and foveal avascular zone.Results: The capillary blood velocity was significantly reduced in both diabetic groups (P