Calcium deficiency alters chorda tympani nerve responses to oral calcium chloride
Calcium deficiency alters chorda tympani nerve responses to oral calcium chloride
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DOI：
10.1016/s0031-9384(97)00387-9
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发表时间：
1998-01-01
影响因子：
2.9
通讯作者：
Tordoff, MG
中科院分区：
文献类型：
--
作者：
Inoue, M;Tordoff, MG
As a preliminary examination of the influence of calcium deficiency on gustatory sensitivity to calcium. we recorded electrophysiological responses of the chorda tympani nerve of calcium-replete and calcium-deprived rats. Relative to rats fed calcium-replete diet, rats fed low calcium diet had lower electrophysiological response thresholds to CaCl2 (300 vs. 30 mu M) and calcium lactate (300 vs. 100 mu M) but not NaCl. The calcium-deprived animals had a greater chorda tympani response to 30, 100 and 300 mu M CaCl2 and 30 and 100 mu M calcium lactate but a smaller chorda tympani response to 30, 100 and 300 mM CaCl2 and to 100 mM MgCl2. A behavioral study using an ascending series of 48-h two-bottle preference tests showed that the threshold for acceptance of CaCl2 was similar to the electrophysiological threshold (310 mu M in replete rats, 100 mu M in calcium-deprived rats). These findings raise the possibility that changes in calcium status influence the perception of calcium, which, in turn, influences calcium intake. (C) 1998 Elsevier Science Inc.
