Validity of Mobility Lab (version 2) for gait assessment in young adults, older adults and Parkinson's disease
Validity of Mobility Lab (version 2) for gait assessment in young adults, older adults and Parkinson's disease
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移动能力实验室（第 2 版）对年轻人、老年人和帕金森病患者步态评估的有效性
DOI：
10.1088/1361-6579/ab4023
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发表时间：
2019-09-01
影响因子：
3.2
通讯作者：
Curtze, Carolin
中科院分区：
文献类型：
--
作者：
Morris, Rosie;Stuart, Samuel;Curtze, Carolin
目的：步态提供了一个敏感的测量老化和神经退行性疾病的迹象。步态的测量正在从实验室环境过渡到使用惯性测量单元的诊所，提供了一种简单且具有成本效益的评估工具。然而，这种评估首先需要对照参考系统进行验证。本研究的目的是在实验室中针对年轻人（n = 18）、老年人（n = 18）和轻度帕金森病患者（n = 21）的压力传感器走道验证APDM移动实验室（ML）系统（版本2）。方法：参与者在压力传感器走道上完成了两分钟的步行，同时佩戴三个传感器（绑在腰椎和双脚上）。然后对系统的输出进行比较。主要结果：总的来说，我们确定ML为步态速度、步长、步长SD、步频、步幅时间和步幅时间SD提供了良好到极好的一致性（ICC > 0.75）。双支撑时间、单支撑时间和挥杆时间的测量结果具有中度至较差的一致性（ICC 0.213-0.725），特别是对于年轻成人和PD。意义：总体而言，Mobility Lab为临床和研究应用提供了一个有效的步态数据收集系统。
Objective: Gait provides a sensitive measurement for signs of aging and neurodegenerative conditions. Measurement of gait is transitioning from the laboratory environment to the clinic with the use of inertial measurement units, providing a simple and cost-effective assessment tool. However, such assessments first need validation against reference systems. The aim of this study was to validate the APDM Mobility Lab (ML) system (version 2) against a pressure sensor walkway in younger adults (n = 18), older adults (n = 18) and people with mild Parkinson's disease (n = 21) in the laboratory. Approach: Participants completed a two-minute walk over a pressure sensor walkway whilst wearing three sensors (strapped to the lumbar spine and both feet). Comparison of output from the systems was then performed. Main results: Overall, we identified that ML provided good to excellent agreement (ICC > 0.75) for gait velocity, stride length, stride length SD, cadence, stride time and stride time SD. Measures of double support time, single support time and swing time had moderate to poor agreement (ICC 0.213-0.725), particularly for younger adults and PD. Significance: Overall, Mobility Lab provides a valid system for gait data collection for clinical and research application.