Cloning and developmental expression patterns of Dlx2, Lhx7 and Lhx9 in the medaka fish (Oryzias latipes)
Cloning and developmental expression patterns of Dlx2, Lhx7 and Lhx9 in the medaka fish (Oryzias latipes)
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DOI：
10.1016/j.mod.2004.03.023
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发表时间：
2004-07-01
影响因子：
2.6
通讯作者：
Rétaux, S
中科院分区：
文献类型：
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作者：
Alunni, A;Blin, M;Rétaux, S
我们从青冈鱼(Oryzias Latipe)中分离到三个同源结构域和LIM同源结构域发育转录因子：OlDlx2、OlLhx7和OlLhx9，并研究了它们在发育中和成体脑中的表达模式。这一分析表明，OlDlx2和OlLhx7(与OlNkx2.1b一起)描绘了青竹端脑的皮质下分裂，OlLhx9在大脑皮层和间脑神经聚体中表现出典型而特殊的表达拓扑。这三个基因的表达模式，当与它们的四足同源物进行详细比较时，揭示了发育中的硬骨鱼和脊椎动物前脑的基本组织的共性和差异。(C)2004爱思唯尔爱尔兰有限公司。保留所有权利。
We have isolated three homeodomain and LIM-homeodomain developmental transcription factors from the medaka fish (Oryzias latipes): OlDlx2, OlLhx7, and OlLhx9, and we have studied their expression patterns in the developing and adult brain. This analysis showed that OlDlx2 and OlLhx7 (together with OlNkx2.1b) delineate the subpallial divisions of the medaka telencephalon, and that OlLhx9 exhibits a typical and specific topology of expression in the pallium and diencephalic neuromeres. The expression patterns of these three genes, when compared in details with those of their tetrapod homologs, reveal both commonalities and differences in the basic organization of the developing teleost and vertebrate forebrain. (C) 2004 Elsevier Ireland Ltd. All rights reserved.