Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021.
Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021.
复制标题
荷兰，荷兰，2月至2021年5月，对SARS-COV-2传播的疫苗有效性和其他确认病例的感染和其他紧密接触。
DOI：
10.2807/1560-7917.es.2021.26.31.2100640
复制
发表时间：
2021-08
期刊：
影响因子：
--
通讯作者：
Members of the RIVM COVID-19 surveillance and epidemiology team
中科院分区：
文献类型：
--
作者：
de Gier B;Andeweg S;Joosten R;Ter Schegget R;Smorenburg N;van de Kassteele J;RIVM COVID-19 surveillance and epidemiology team 1,;Hahné SJ;van den Hof S;de Melker HE;Knol MJ;Members of the RIVM COVID-19 surveillance and epidemiology team
一些研究报告了COVID-19疫苗对SARS-CoV-2感染和严重疾病的高有效性，但一个重要的知识空白是疫苗的抗传播有效性（VET）。我们利用接触者监测数据，提出了2021年2月至5月荷兰家庭和其他密切接触者的职业教育培训估计值。完全接种疫苗的家庭接触者的继发发病率低于未接种疫苗的指数病例（11%对31%），调整后的VET为71%（95%置信区间：63-77）。
Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63–77).