Drugs and group psychotherapy in neurotic depression.
Drugs and group psychotherapy in neurotic depression.
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神经症抑郁症的药物和团体心理治疗。
DOI：
10.1176/ajp.131.2.191
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发表时间：
1974
期刊：
影响因子：
--
通讯作者：
J. H. Pattison
中科院分区：
文献类型：
--
作者：
L. Covi;Ronald S. Lipman;Leonard R. Derogates;James E. Smith;J. H. Pattison
经过两周的安慰剂洗脱期后，慢性抑郁神经症门诊女性患者被随机分配接受三种药物（丙咪嗪、地西泮或安慰剂）中的一种，并在两个诊所中的一个接受每周一次的团体心理治疗或两周一次的简短支持疗程。前16周积极治疗的协方差分析（N = 146）表明丙咪嗪在大多数结果测量上具有显著的治疗优势。在这些措施中没有发现团体治疗的优势。出现改善的患者继续接受进一步的对照药物治疗，总共71周；这一阶段的初步分析显示丙咪嗪治疗有一些持续的优势。
Chronically depressed neurotic women outpatients were randomly assigned, after a two-week placebo washout period, to receive one of three medications (imipramine, diazepam, or placebo) and to either weekly group psychotherapy or biweekly brief supportive sessions at one of two clinics. Analyses of covariance for the first 16 weeks of active treatment (N = 146) indicated a marked therapeutic advantage for imipramine on most of the outcome measures. No advantage for group therapy was detected on these measures. Patients who showed improvement were continued in further controlled drug treatment for up to a total of 71 weeks; preliminary analyses of this phase showed some continuing advantage for treatment with imipramine.