FOCUS ON CURRENT TRENDS IN THE TREATMENT OF HELICOBACTER PYLORI INFECTION: AN UPDATE Review Article

FOCUS ON CURRENT TRENDS IN THE TREATMENT OF HELICOBACTER PYLORI INFECTION: AN UPDATE Review Article
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关注幽门螺杆菌感染治疗的当前趋势:更新综述文章

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发表时间:
2011
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影响因子:
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通讯作者:
N. Rao
N. Rao
中科院分区:
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作者:
N. Rao

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幽门螺杆菌感染是影响全世界人口的最脆弱的胃肠道感染之一。它可引起胃炎、胃十二指肠溃疡、胃癌和原发性胃b细胞淋巴瘤等复杂的胃病。目前国际指南提出的用于减轻这种慢性破坏性细菌感染的剂量方案(两种抗生素(克拉霉素加阿莫西林或甲硝唑)与PPI联合使用至少7天以根除幽门螺杆菌)仍被发现不能令人满意。因此,需要一个小时来设计和开发替代药物输送系统,即胃保留输送系统,特定部位输送系统和益生菌。本文综述了与幽门螺杆菌感染的诊断和治疗有关的问题,包括草药配方。
One of the most vulnerable gastro intestinal tract infections affecting the human population worldwide are H pylori infections. It causes complicated gastric problems such as gastritis, gastro duodenal ulcers, gastric cancer and primary B-cell gastric lymphoma. The current dosage regimens proposed by the international guidelines which are in practice to abate this chronic destructive bacterial infection (combination of two antibiotics (clarithromycin plus amoxicillin or metronidazole) with a PPI for at least 7 days for the eradication of H pylori) were still found to be unsatisfactory. So there is a need of hour to design and develop alternative drug delivery systems viz. gastro retentive delivery systems, site specific delivery systems and probiotics. This review focuses the issues related to the diagnosis and treatment of H pylori infection including herbal formulations.
生姜 (Zingiber officinale Roscoe) 和姜辣素可抑制幽门螺杆菌 Cag A 菌株的生长。
DOI: --
发表时间: 2003
影响因子: 2
作者:
Mahady,GailB;Pendland,SusanL;Yun,GinaS;Lu,Zhi-Zhen;Stoia,Adina
通讯作者: Stoia,Adina