Synthesis of ethyl 2-aminodihydro-5-pyrimidinecarboxylate derivatives and 3,7-diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-1 H-pyrimido[1,2-a]pyrimidines
Synthesis of ethyl 2-aminodihydro-5-pyrimidinecarboxylate derivatives and 3,7-diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-1 H-pyrimido[1,2-a]pyrimidines
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DOI：
10.1002/jhet.5570340152
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发表时间：
1997-01-01
影响因子：
2.4
通讯作者：
Vaissermann, J
中科院分区：
文献类型：
--
作者：
Milcent, R;Malanda, JC;Vaissermann, J
研究了 3-芳基-2-苯甲酰基丙烯酸乙酯 1 与胍和 N-烷基（或苄基）胍的反应。合成了2-氨基二氢-5-嘧啶甲酸乙酯衍生物3、4或5，以及3,7-二乙氧基羰基-4,6-二氢-2,4,6,8-四芳基-1H-嘧啶醇[1,2-a]嘧啶6。
Reactions of ethyl 3-aryl-2-benzoylpropenoates 1 with guanidine and N-alkyl(or benzyl)guanidines have been investigated. Ethyl 2-aminodihydro-5-pyrimidinecarboxylate derivatives 3, 4 or 5, and 3,7-diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-1H-pyrimidol[1,2-a]pyrimidines 6 have been synthesized.