"The Promise of Community-Based Advocacy and Education Efforts for Increasing Cancer Clinical Trials Accrual"
"The Promise of Community-Based Advocacy and Education Efforts for Increasing Cancer Clinical Trials Accrual"
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DOI：
10.1007/s13187-011-0271-6
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发表时间：
2012-03-01
影响因子：
1.6
通讯作者：
Patel, Shilpa
中科院分区：
文献类型：
--
作者：
Michaels, Margo;Weiss, Elisa S.;Patel, Shilpa
只有 3% 的癌症患者参加癌症临床试验 (CCT)。通过以社区为中心的教育和宣传工作，可以解决一些参与障碍，特别是少数群体的参与障碍。一项试点计划与社区合作伙伴合作，旨在改变社区领导、初级保健提供者 (PCP) 和临床研究人员关于 CCT 的知识、态度和角色行为，以提高患者对 CCT 的认识和参与。混合方法评估利用了项目期间（2006-2008）对参与者进行的调查的定量分析以及对主要参与者访谈的定性数据。计划工作有效地增加了知识并培训社区领导和 PCP 传播有关临床试验的信息，并最终增加了患者对当地试验的询问。培训提高了临床研究人员的文化能力技能，以招募和留住 CCT 参与者。伙伴关系培育了新的流程和结构，以促进 CCT 参与其社区。通过社区伙伴关系进行的临床试验教育和宣传工作对于提高临床试验的可及性和增加临床试验的参与具有重要作用。肿瘤学家参与和领导此类伙伴关系对于促进 CCT 累积至关重要，特别是对于少数群体而言。
Only 3% of cancer patients participate in cancer clinical trials (CCTs). A number of barriers to participation, particularly for minority groups, can be addressed through community-focused education and advocacy efforts. Working with community partnerships, a pilot program sought to change knowledge, attitudes, and role behaviors among community leaders, primary care providers (PCPs), and clinical researchers about CCTs, to increase patient awareness of and participation in CCTs. A mixed method evaluation utilized quantitative analysis of surveys administered to participants during the program period (2006-2008) and qualitative data from interviews with key participants. Programmatic efforts were effective in increasing knowledge and training community leaders and PCPs to disseminate messages about clinical trials, and ultimately increasing patient inquiries about local trials. Training improved cultural competency skills among clinical researchers to recruit and retain CCT participants. Partnerships fostered new processes and structures to facilitate CCT participation in their communities. Clinical trials education and advocacy efforts through community partnerships have an important role in enhancing clinical trial access and in increasing clinical trial participation. Oncologists' involvement in and leadership of such partnerships are critical to promoting CCT accrual, particularly for minority groups.