Measurements of biomagnetic fields using a high-resolution dc superconducting quantum interference device magnetometer
Measurements of biomagnetic fields using a high-resolution dc superconducting quantum interference device magnetometer
复制标题
使用高分辨率直流超导量子干涉装置磁力计测量生物磁场
DOI：
10.1063/1.367739
复制
发表时间：
1998
影响因子：
3.2
通讯作者：
S. Nakayama
中科院分区：
文献类型：
--
作者：
K. Iramina;B. Hong;S. Uchida;K. Goto;S. Ueno;S. Nakayama
我们研制了一种用于测量小动物生物磁场的多通道高分辨率超导量子干涉装置磁强计。我们测量了大鼠产生的心磁图。记录大鼠心磁图P波、QRS波和T波的形态。我们还测量了大鼠的视网膜磁图、视觉诱发磁场和听觉诱发磁场。视网膜磁图信号潜伏期为60ms，场强约为0.6pT。由于这些信号隐藏在视网膜磁图之后，因此不可能获得清晰的视觉诱发场。实验结果表明，大鼠听觉诱发磁场是可能的。在右耳两侧观察到波形的显着差异，这是由15 mm分离。我们的系统具有足够的空间分辨率测量心磁图和听觉诱发磁场产生的小动物。
We have developed a multichannel high-resolution superconducting quantum interference device magnetometer for measuring biomagnetic fields produced by small animals. We measured the magnetocardiogram produced by a rat. Topographies of the P wave, QRS wave, and T wave of the rat magnetocardiogram were obtained. We also measured the magnetoretinogram, visually evoked magnetic fields, and auditory evoked magnetic fields of the rat. The signals of the magnetoretinogram appeared at 60 ms latency and the field intensities were about 0.6 pT. It was not possible to obtain the clear visually evoked fields because those signals were hidden behind the magnetoretinogram. It was possible to obtain auditory evoked magnetic fields of the rat. The significant differences of the wave forms were observed in both sides of the right ear, which are separated by 15 mm. Our system has adequate spatial resolution for measurement of the magnetocardiogram and auditory evoked magnetic fields produced by small animals.