Adaptation to eccentric exercise: effect on CD64 and CD11b/CD18 expression.
Adaptation to eccentric exercise: effect on CD64 and CD11b/CD18 expression.
复制标题
适应离心运动:对 CD64 和 CD11b/CD18 表达的影响。
DOI:
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发表时间:
1996
影响因子:
3.3
通讯作者:
Thomas A. Naglieri
中科院分区:
文献类型:
--
作者:
F. Pizza;Bruce H. Davis;S. D. Henrickson;Joel B. Mitchell;J. F. Pace;N. Bigelow;P. C. DiLauro;Thomas A. Naglieri
The primary purpose of the study was to examine circulating neutrophils and monocytes and their plasma membrane expression of CD64, CD11b, and CD18 after two bouts (B1 and B2) of eccentric exercise. Subjects (n = 10) performed 25 forced-lengthened contractions of the forearm flexors on two occasions separated by 3 wk. Blood samples were obtained before exercise and at 1.5, 6, 12, 24, 48, 72, and 96 h of recovery. CD64, CD11b, and CD18 expression was determined via direct immunofluorescence and used as an indicator of neutrophil and monocyte activation. Creatine kinase activity (B1 = 1,390, B2 = 108 U/l), myoglobin (B1 = 163, B2 = 41, ng/dl), and muscle soreness and tenderness were higher (P < 0.01) after B1 compared with B2. Neutrophils at 6, 12, and 96 h were higher (P < 0.05) for B1 vs. B2. CD11b expression on neutrophils was 2.7-fold higher at 72 h for B1 vs. B2. CD64 expression on neutrophils at 72 and 96 h was 1.4- and 1.9-fold higher, respectively, for B1 vs. B2. At 72 and 96 h, CD18 and CD64 expression on monocytes was 1.3-fold higher for B1 vs. B2. The observed changes were not significantly correlated with changes in creatine kinase activity or myoglobin. In conclusion, the adaptation to eccentric arm exercise was associated with a reduction in circulating neutrophils and a lower state of neutrophil and monocyte activation.
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DOI:
--
发表时间:
1987
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Perussia,B;Kobayashi,M;Rossi,ME;Anegon,I;Trinchieri,G
通讯作者:
Trinchieri,G
DOI:
10.1152/ajpheart.1989.257.4.h1068
发表时间:
1989
期刊:
The American journal of physiology
影响因子:
--
作者:
Yokota,J;Minei,JP;Fantini,GA;Shires,GT
通讯作者:
Shires,GT
影响因子:
4.1
作者:
Robert B. Armstrong
通讯作者:
Robert B. Armstrong
影响因子:
20.3
作者:
Akerley3rd,WL;Guyre,PM;Davis,BH
通讯作者:
Davis,BH
DOI:
--
发表时间:
1987
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
--
作者:
Shen,L;Guyre,PM;Fanger,MW
通讯作者:
Fanger,MW