The homeotic gene spalt (sal) evolved during Drosophila speciation.
The homeotic gene spalt (sal) evolved during Drosophila speciation.
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同源异型基因 spalt (sal) 在果蝇物种形成过程中进化。
DOI：
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发表时间：
1989
影响因子：
11.1
通讯作者：
H. Jäckle
中科院分区：
文献类型：
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作者：
D. Reuter;R. Schuh;H. Jäckle
区域特异性同源异型基因spalt（sal）在果蝇胚胎的头部和尾部区域的两个独立的结构域中起作用。基于比较形态学，在无脊椎动物的进化过程中，sal可能参与了头部的建立，因此，它应该被保护。我们已经分析了几个果蝇物种中的分割基因Krüppel（Kr）和even-skipped（eve）的保守性，这些果蝇物种在进化上相隔长达6000万年。令我们惊讶的是，sal序列似乎是保守的果蝇属的Sophophora亚属，但不是在果蝇亚属。另一方面，在果蝇亚群中，体节和其他同源异型基因也是保守的。我们的数据表明，sal编码一个辅助功能，在果蝇物种形成过程中相对较晚，而不是发挥基本的进化作用类似于其他同源异型基因。
The region-specific homeotic gene spalt (sal) acts in two separate domains in the head and tail region of the Drosophila melanogaster embryo. Based on comparative morphology, sal is likely to be involved in the establishment of the head during the evolution of invertebrates and thus, it should be conserved. We have analyzed the conservation of the segmentation genes Krüppel (Kr) and even-skipped (eve) in parallel with sal coding sequences in several Drosophila species that are evolutionarily separated by up to 60 million years. To our surprise, sal sequences appear to be conserved in the Sophophora subgenus of the Drosophila genus but not in the Drosophila subgenus. On the other hand, the segmentation and other homeotic genes are conserved in the Drosophila subgroup as well. Our data suggest that sal encodes an accessory function that evolved relatively late during Drosophila speciation rather than playing a fundamental evolutionary role similar to that of other homeotic genes.