Synthesis and properties of a novel fluorescent nucleobase, naphthopyridopyrimidine

Synthesis and properties of a novel fluorescent nucleobase, naphthopyridopyrimidine
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DOI:
10.1016/s0040-4039(03)01740-4
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发表时间:
2003-09-01
影响因子:
1.8
通讯作者:
Saito, I
Saito, I
中科院分区:
化学4区
文献类型:
--
作者:
Okamoto, A;Tainaka, K;Saito, I

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本文描述了一种新的碱基识别荧光核苷NPP,它能在与NPP相对的A碱基和G碱基之间做出清晰的区分。含有NPP的ODN探针与靶DNA杂交有助于判断位于靶DNA上特定位置的嘌呤碱基的类型。(C)2003年,爱思唯尔有限公司出版。
A new base-discriminating fluorescent nucleoside, NPP, that can sharply distinguish between A and G bases opposite NPP is described. The hybridization of an ODN probe containing NPP with a target DNA facilitates the judgment of the type of purine base located at a specific site on the target DNA. (C) 2003 Published by Elsevier Ltd.