Safety and effectiveness of predeposit autologous transfusions in preteen and adolescent children.
Safety and effectiveness of predeposit autologous transfusions in preteen and adolescent children.
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青春期前和青春期儿童预存自体输血的安全性和有效性。
DOI：
10.1001/jama.1987.03390240109034
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发表时间：
1987
期刊：
影响因子：
--
通讯作者：
A. Silvergleid
中科院分区：
文献类型：
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作者：
A. Silvergleid
尽管文献中有关于考虑手术的成年患者预置自体输血的安全性和有效性的记录，但对于青春期前和青少年儿童没有可比较的数据。我们报告了 180 名 8 至 18 岁儿童参与基于社区血液中心的预存自体输血计划的经验。年仅 8 岁、体重仅 27 公斤的儿童在选择性骨科 (169) 或整形 (11) 手术之前预先捐献了规定量的血液。只有四个孩子经历了捐赠者反应；没有一个是严重的。没有孩子无法捐赠规定数量的单位。百分之八十八的儿童能够满足他们的全血需求，从而避免接触同源血液。我们的经验证明了预存自体输血在青春期前和青春期儿童中的安全性和有效性，并应鼓励现有的预存自体输血计划将参与范围扩大到数千名目前无法使用自己血液的儿童。
Although there is documentation in the literature of the safety and effectiveness of predeposit autologous transfusions among adult patients contemplating surgery, there are no comparable data for preteen and teenage children. We report our experience with 180 children between the ages of 8 and 18 years participating in a community blood center-based predeposit autologous transfusion program. Children as young as 8 years old and weighing as little as 27 kg predonated a prescribed amount of blood prior to elective orthopedic (169) or plastic (11) surgery. Only four children experienced a donor reaction; none of them was severe. No child was unable to donate the prescribed number of units. Eighty-eight percent of the children were able to supply their complete blood requirements, thus avoiding exposure to homologous blood. Our experience documents both the safety and effectiveness of predeposit autologous transfusions in preteen and adolescent children and should encourage existing predeposit autologous transfusion programs to extend participation to thousands of children for whom the opportunity to use their own blood is currently denied.