The distribution of periodontopathic bacteria among Japanese children and their parents
The distribution of periodontopathic bacteria among Japanese children and their parents
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DOI：
10.1111/j.1600-0765.2004.00754.x
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发表时间：
2004-12-01
影响因子：
3.5
通讯作者：
Ishikawa, I
中科院分区：
文献类型：
--
作者：
Umeda, M;Miwa, Z;Ishikawa, I
目的和背景：目前尚不清楚牙周病细菌在儿童时期如何在口腔中定殖。本研究的目的是调查儿童及其家长口腔中牙周病细菌的分布情况以及细菌结果与临床参数之间的关系。方法：56名儿童（平均年龄：8.3±3.5岁，范围：1-15岁）及其父母参与了本研究，其中乳牙列15例，混合牙列26例，恒牙列15例。采集儿童全唾液、牙菌斑及家长全唾液，采用聚合酶链反应法检测7种牙周病菌（伴放线放线杆菌、福赛坦氏杆菌、直肠弯曲杆菌、牙龈卟啉单胞菌、中间普雷沃菌、黑普氏菌、齿垢密螺旋体）。记录患儿及其家长的简化口腔卫生指数、乳头边缘附着指数等临床参数。结果：儿童口腔中连翘毛霉、直肠毛霉、黑毛霉、齿毛毛霉、放线菌、牙龈毛霉的检出率分别为42.9%、94.6%、42.9%。分别为 48.2%、1.8% 和 8.9%。连翘、牙龈卟啉单胞菌和齿垢毛滴虫在父母唾液中的检出率（分别为 54.8%、54.8%、88.1%）高于儿童唾液（分别为 25.5%、7.3%、41.8%）。在乳牙列、混合牙列和恒牙列儿童的口腔中，黑曲霉的检出率存在差异。在混合牙列中，女性比男性更容易携带连翘毛虫。在乳牙列、混合牙列和恒牙列儿童的口腔中发现了连翘木、中间木霉、黑木霉的儿童。在混合牙列中，女性比男性更容易携带连翘毛虫。携带连翘、中间松、黑松和齿垢的儿童在简化口腔卫生指数的口腔残渣测量中得分较高。 T. forsythensis、P. intermedia 和 P. nigrescens 在这些病原体的父母呈阳性的儿童中比在父母呈阴性的儿童中更常见。结论：高菌斑保留似乎促进了牙周病原体在儿童口腔中的定植。如果父母已经携带这些细菌，则在儿童的口腔中更容易检测到连翘毛霉、中间毛霉和黑毛霉。建议这些细菌存在家族传播。
Objective and background: It is not well known how periodontopathic bacteria colonize in the oral cavity during childhood. The purpose of this study was to investigate the distribution of periodontopathic bacteria in oral cavities of children and their parents and the relationship between the bacterial findings and clinical parameters.Methods: Fifty-six children (mean age: 8.3 +/- 3.5, range: 1-15 years), including 15 with deciduous dentition, 26 with mixed dentition and 15 with permanent dentition, and their parents participated in this study. Whole saliva and dental plaque of the children and whole saliva of their parents were collected for detection of seven species of periodontopathic bacteria (Actinobacillus actinomycetemcomitans, Tannerella forsythensis (Bacteroides forsythus), Campylobacter rectus, Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Treponema denticola) using the polymerase chain reaction method. Clinical parameters including simplified Oral Hygiene Index and Papillary-Marginal-Attachment Index were recorded for the children and their accompanied parents.Results: The detection frequencies of T. forsythensis, C. rectus, P. nigrescens, T. denticola, A. actinomycetemeomitans and P. gingivalis in the oral cavities of children were 42.9%, 94.6%, 42.9%, 48.2%, 1.8% and 8.9%, respectively. T. forsythensis, P. gingivalis and T. denticola were detected more frequently in the saliva of parents (54.8%, 54.8%, 88.1%, respectively) than in the saliva of children (25.5%, 7.3%, 41.8%, respectively). Different detection frequencies of P. nigrescens were found among the oral cavities of children with deciduous, mixed and permanent dentitions. In mixed dentition, females harbored T. forsythensis more frequently than males did. Children who harbored T. forsythensis, P. intermedia, P. nigrescens were found among the oral cavities of children with deciduous, mixed and permanent dentitions. In mixed dentition, females harbored T. forsythensis more frequently than males did. Children who harbored T. forsythensis, P. intermedia, P. nigrescens and T. denticola showed high scores for oral debris measurement by simplified Oral Hygiene Index. T. forsythensis, P. intermedia and P. nigrescens were detected more frequently in children whose parents were positive for these pathogens than in children whose parents were negative.Conclusions: High plaque retention seems to promote the colonization of periodontal pathogens in the oral cavities of children. T. forsythensis, P. intermedia and P. nigrescens were detected more frequently in the oral cavities of children whose parents already harbored these bacteria. Familial transmission of these bacteria is suggested.