A common plan for dorsoventral patterning in Bilateria
A common plan for dorsoventral patterning in Bilateria
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DOI：
10.1038/380037a0
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发表时间：
1996-03-07
期刊：
影响因子：
64.8
通讯作者：
Sasai, Y
中科院分区：
文献类型：
--
作者：
DeRobertis, EM;Sasai, Y
功能研究现在似乎证实，正如E.Geoffroy Saint-Hilaire在1822年首次提出的那样，在动物进化过程中存在背腹轴的倒置。在果蝇和脊椎动物中，一个保守的细胞外信号系统为胚胎细胞分配到特定组织类型提供了位置信息；果蝇的腹侧区域与脊椎动物的背侧同源。发育研究现在揭示了产生节肢动物和哺乳动物血统的祖先动物的一些特征，我们建议将其命名为Urbilateria。
Functional studies seem now to confirm, as first suggested by E. Geoffroy Saint-Hilaire in 1822, that there was an inversion of the dorsoventral axis during animal evolution. A conserved system of extracellular signals provides positional information for the allocation of embryonic cells to specific tissue types both in Drosophila and vertebrates; the ventral region of Drosophila is homologous to the dorsal side of the vertebrate. Developmental studies are now revealing some of the characteristics of the ancestral animal that gave rise to the arthropod and mammalian lineages, for which we propose the name Urbilateria.