Crystallization of an Lhx3-Isl1 complex
Crystallization of an Lhx3-Isl1 complex
复制标题
DOI：
10.1107/s174430910800691x
复制
发表时间：
2008-04-01
影响因子：
0.9
通讯作者：
Matthews, Jacqueline Mary
中科院分区：
文献类型：
--
作者：
Bhati, Mugdha;Lee, Mihwa;Matthews, Jacqueline Mary
一个稳定的分子内复合体，包括LIM-同源结构域蛋白Lhx3的LIM结构域连接到Is11的肽区，已经被设计、纯化和结晶。单斜晶属空间群C2，晶胞参数a = 119, b = 62.2, c = 51.9埃，β = 91.6度，衍射分辨率为2.05埃。
A stable intramolecular complex comprising the LIM domains of the LIM-homeodomain protein Lhx3 tethered to a peptide region of Is11 has been engineered, purified and crystallized. The monoclinic crystals belong to space group C2, with unit-cell parameters a = 119, b = 62.2, c = 51.9 angstrom, beta = 91.6 degrees, and diffract to 2.05 angstrom resolution.