Correlation between MRI and histopathologic findings in stage I cervical carcinomas: influence of stromal desmoplastic reaction
Correlation between MRI and histopathologic findings in stage I cervical carcinomas: influence of stromal desmoplastic reaction
复制标题
DOI：
10.1136/ijgc-00009577-200603000-00023
复制
发表时间：
2004-12
期刊：
影响因子：
--
通讯作者：
K. Itoh;T. Shiozawa;S. Ohira;S. Shiohara;I. Konishi
中科院分区：
文献类型：
--
作者：
K. Itoh;T. Shiozawa;S. Ohira;S. Shiohara;I. Konishi
尽管磁共振成像 (MRI) 在描述宫颈癌方面的有效性已有报道，但 MRI 是否可以检测早期或 IB 期“隐匿”型宫颈癌仍不确定。我们检查了 38 例 I 期（IB 28 例，IA 10 例）宫颈癌患者的 MRI 与病理结果之间的相关性，特别关注肿瘤周围促纤维增生性基质反应的影响。结果表明，MRI 在 IA 期患者中没有检测到肿瘤，但在 21 名 (75%) IB 期患者中检测到肿瘤。 18 个直径超过 2 cm 的肿瘤中的 15 个 (83%) 和 10 个 2 cm 或更小的肿瘤中的 6 个 (60%) 清晰地显示了图像。 22 个肿瘤中有 21 个 (95%) 具有显着 (>200 μ) 基质反应，但 6 个肿瘤中没有一个具有最小 (≤200 μ) 基质反应。这些发现表明 MRI 对于检测 IA 期肿瘤没有用。然而，在 IB 期肿瘤中，基质反应而不是肿瘤的大小可能影响肿瘤在 MRI 中的图像。
Although the effectiveness of magnetic resonance imaging (MRI) in depicting cervical carcinoma has been reported, whether MRI can detect early-stage or stage IB “occult”-type cervical carcinoma remained undetermined. We examined the correlation between MRI and pathologic findings in 38 stage I (IB 28 cases, IA 10 cases) cervical carcinoma patients, with special reference to the influence of desmoplastic stromal reaction around the tumor. The results demonstrated that the tumor was detected by MRI in none of stage IA patients but in 21 (75%) stage IB patients. The image was clearly demonstrated in 15 of 18 (83%) tumors of more than 2 cm in diameter and in 6 of 10 (60%) tumors of 2 cm or less. The tumor image was evident in 21 of 22 (95%) tumors with prominent (>200 μ) stromal reaction but in none of 6 tumors with minimal (≤200 μ) stromal reaction. These findings suggest that MRI is not useful for the detection of stage IA tumors. In stage IB tumors, however, the stromal reaction rather than the size of the tumor may influence the tumor's image in MRI.