Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus
Reevaluation of the role of HWP1 in systemic candidiasis by use of Candida albicans strains with selectable marker URA3 targeted to the ENO1 locus
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DOI：
10.1128/iai.70.6.3281-3283.2002
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发表时间：
2002-06-01
影响因子：
3.1
通讯作者：
Staab, JF
中科院分区：
文献类型：
--
作者：
Sundstrom, P;Cutler, JE;Staab, JF
先前对HWP1在CBA/J小鼠系统性念珠菌病中的评估是用URA3基因位置不同的白色念珠菌菌株进行的，这是由于Ura-Blaster突变的结果。在这项研究中，HWP1的存在和UP，43的位置与BALB/c小鼠系统性念珠菌病的严重程度有关。
Previous evaluation of HWP1 in systemic candidiasis in CBA/J mice was done with Candida albicans strains with differing genetic locations of URA3 as a result of Ura-blaster mutagenesis. In this study, the presence of HWP1 and the location of UP,43 contributed to the severity of murine systemic candidiasis in BALB/c mice.