Assessment of surgical outcomes and oncological safety for submental artery perforator flap reconstruction after ablation of oral cancer
Assessment of surgical outcomes and oncological safety for submental artery perforator flap reconstruction after ablation of oral cancer
复制标题
口腔癌消融后颏下动脉穿支皮瓣重建的手术结果和肿瘤学安全性评估
DOI：
10.1016/j.bjoms.2020.08.120
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发表时间：
2021-10-01
影响因子：
1.8
通讯作者：
Jiang, C.
中科院分区：
文献类型：
--
作者：
Shen, Z. Z.;Lu, C.;Jiang, C.
颏下动脉穿支皮瓣（submenarterialperforatorflap，SAPF）是近年来口腔鳞状细胞癌（oralsquamouscellcarcinoma，OSCC）患者口腔修复的一种新方法，但其手术效果尚未得到很好的评价。我们比较了传统颏下岛状皮瓣（SIF）和股前外侧穿支皮瓣（ALTPF）在原发性口腔癌消融术后SAPF重建中等大小软组织缺损的手术结局和肿瘤安全性。从我们的机构临床肿瘤学数据库中回顾了51例SAPF、30例SIF和74例ALTPF用于口腔癌消融后的口腔内中等大小重建。我们对3个队列的手术结局和肿瘤安全性变量进行了比较评估。Kaplan-Meier估计每个皮瓣的存活率。与ALTPF相比，SIF和SAPF组的手术时间显著缩短（分别为p = 0.021和0.014）。SAPF组皮瓣厚度最薄，平均0.5cm。两组供区并发症均为切口裂开和口瘘。3组间无病生存期（DFS）无显著差异。然而，几个口腔鳞状细胞癌患者的SIF重建被发现有复发与转移淋巴结下的皮瓣后，第一次手术。SAPF可作为口腔癌切除术后中等大小软组织缺损的口腔内修复的一种通用选择。(c)2020年英国口腔颌面外科医生协会。由爱思唯尔有限公司出版。保留所有权利。
The submental artery perforator flap (SAPF) has been a new option for the intraoral reconstruction of oral squamous cell carcinoma (OSCC) patients in recent years, but its surgical outcomes have not been well assessed. We compared the surgical outcomes and oncological safety of SAPF reconstruction for medium-sized soft-tissue defects after the ablation of primary oral cancer with traditional submental island flaps (SIF) and anterolateral thigh perforator flaps (ALTPF). Fifty-one SAPF, 30 SIF, and 74 ALTPF were reviewed for the intraoral medium-sized reconstructions after the ablation of oral cancer from our institutional clinical oncological databases. We performed comparative assessments on the variables of surgical outcome and oncological safety among the 3 cohorts. A Kaplan-Meier estimate of survival for each flap was calculated. Operating time was significantly reduced in the SIF and SAPF groups than ALTPF (p = 0.021 and 0.014, respectively). Flap thickness of SAPF was the significantly thinnest (mean 0.5 cm) among three groups. The common complications of donor site for both SAPF and SIF group were incision dehiscence and orocutaneous fistula. There was no significant difference in disease-free survival (DFS) among the 3 groups. However, several OSCC patients with the SIF reconstruction were found to have recurrences with a metastatic lymph node under the flap after the first operation. SAPF could be a versatile choice of the intraoral reconstruction for the medium-sized soft-tissue defects after the ablation of oral cancer. (c) 2020 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.