[Venous leg ulcer].
[Venous leg ulcer].
复制标题
[腿部静脉性溃疡]。
DOI：
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发表时间：
1997
期刊：
影响因子：
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通讯作者：
L. Danielsen
中科院分区：
文献类型：
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作者：
B. Hamilton Jakobsen;L. Danielsen
本文综述了目前对静脉性小腿溃疡的看法。静脉性溃疡是一种需要资源的疾病，影响1%的人口。浅表和/或深静脉功能不全合并踝部穿支功能不全。发病机制仍有争议，但推测与毛细血管渗漏、血液成分渗漏和随后的脂肪皮肤病以及多发性毛细血管血栓有关。不适当的白细胞激活也可能起到一定作用。压迫稳定毛细血管功能，因此是治愈和预防的主要治疗方法。在90%的病例中，只要深静脉不受影响，浅静脉手术后就不会复发。在深静脉功能不全的患者中，此类手术后失败的风险，包括穿支切除，与功能不全的程度有关。如果常规治疗失败，可以考虑重建深静脉。伴随的情况，如动脉供血不足和全身疾病，使治疗变得困难，铜绿假单胞菌的存在在某些情况下可能会推迟愈合。
The article summarizes current views regarding venous leg ulcers. Venous ulcers are resource-demanding and affect 1% of the population. Superficial and/or deep venous insufficiency is to be found combined with perforator insufficiency in the ankle are. The pathogenesis is still open to debate, but is presumably related to capillary leakage, with seepage of blood components and ensuing lipodermatosclerosis, as well as to multiple capillary thromboses. Inappropriate leucocyte activation might also play a part. Compression stabilizes capillary function and thus is the cardinal treatment both regarding healing and prophylaxis. In 90% of cases there is no recurrence following superficial vein surgery, so long as the deep veins remain unaffected. In patients with deep venous insufficiency the risk of failure following-such surgery, perforator resection included, is related to the degree of insufficiency. If conventional treatment fails, reconstruction of the deep veins may be considered. Concomitant conditions such as arterial insufficiency and systemic diseases make treatment difficult, and the presence of Pseudomonas aeruginosa may in certain cases delay healing.