Treatment of hepatic coma by exchange blood transfusion.
Treatment of hepatic coma by exchange blood transfusion.
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通过换血治疗肝昏迷。
DOI：
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发表时间：
1966
影响因子：
158.5
通讯作者：
S. Saunders
中科院分区：
文献类型：
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作者：
C. Trey;D. Burns;S. Saunders
近年来，许多出版物都涉及肝性昏迷的发病机制和治疗。与肝功能衰竭相关的神经系统紊乱的多变性和特异性神经病理结果的缺失提示“肝性昏迷”的起源是代谢性的尽管氮代谢紊乱以及氨和胺对脑细胞的影响与这种脑病的发病机制有关，但很明显，这种综合征不是由任何单一因素引起的。然而，对这些病人的治疗是基于已知的生化异常3，包括从饮食中消除所有蛋白质…
IN recent years numerous publications have dealt with the pathogenesis and treatment of hepatic coma. The protean nature of the neurologic disturbances associated with liver failure and the absence of specific neuropathological findings suggest that "hepatic coma" is metabolic in origin.1 Although deranged nitrogen metabolism and the effects of ammonia and amines on brain cells have been implicated in the pathogenesis of this encephalopathy2 it is clear that the syndrome is not due to any single agent. However, the management of these patients is based upon the known biochemical abnormalities3 and includes the elimination of all protein from the diet . . .