Event-related potentials reflect spectral differences in speech and non-speech stimuli in children and adults
Event-related potentials reflect spectral differences in speech and non-speech stimuli in children and adults
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DOI：
10.1016/j.clinph.2008.03.005
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发表时间：
2008-07-01
影响因子：
4.7
通讯作者：
Townsend, J.
中科院分区：
文献类型：
--
作者：
Ceponiene, R.;Torki, M.;Townsend, J.
目的：事件相关脑电位（event - relevant brain potential， ERP）可作为检测正常和异常语言发育的工具。为了阐明听觉ERP的功能意义，我们研究了语音和非语音频谱差异的ERP指数。方法：三个谱项（BA、DA、GA）以音节、非语音和声母转换（CVT）三种刺激类型呈现。14名7 ~ 10岁儿童和14名成人被刺激类型阻断了等概率光谱项目序列。结果：谱项效应表现为P1、P2、N2、N4的幅度变化。两组P2对所有刺激类型均敏感。在成人中，PI对过渡也很敏感，而N4对音节很敏感。在儿童中，只有50ms CVT刺激引起N2和N4谱效应。在两组中，非语音刺激引起更大的N1-P2波幅，而语音刺激引起更大的N2-N4波幅。结论：听觉特征加工由P1-P2和N2-N4峰反映，其成熟早于超感觉统合机制，由N1-P2峰反映。听觉P2似乎与两种处理类型有关。意义：这些结果描述了一个有序的加工组织，其中直接特征映射发生在加工的早期，部分用于声音检测，而关系映射发生在加工的后期，用于声音识别。由爱思唯尔爱尔兰有限公司代表国际临床神经生理学联合会出版。
Objective: Event-related brain potentials (ERP) may provide tools for examining normal and abnormal language development. To clarify functional significance of auditory ERPs, we examined ERP indices of spectral differences in speech and non-speech sounds.Methods: Three Spectral Items (BA, DA, GA) were presented as three Stimulus Types: syllables, non-phonetics, and consonant-vowel transitions (CVT). Fourteen 7- to 10-year-old children and 14 adults were presented with equiprobable Spectral Item sequences blocked by Stimulus Type.Results: Spectral Item effect appeared as P1, P2, N2, and N4 amplitude variations. The P2 was sensitive to all Stimulus Types in both groups. In adults, the PI was also sensitive to transitions while the N4 was sensitive to syllables. In children, only the 50-ms CVT stimuli elicited N2 and N4 spectral effects. In both groups, non-phonetic stimuli elicited larger N1-P2 amplitudes while speech stimuli elicited larger N2-N4 amplitudes.Conclusions: Auditory feature processing is reflected by P1-P2 and N2-N4 peaks and matures earlier than supra-sensory integrative mechanisms, reflected by N1-P2 peaks. Auditory P2 appears to pertain to both processing types.Significance: These results delineate an orderly processing organization whereby direct feature mapping occurs earlier in processing and, in part, serves sound detection whereas relational mapping occurs later in processing and serves sound identification. Published by Elsevier Ireland Ltd. on behalf of Internationl Federation of Clinical Neurophysiology.