Cytologically negative carcinomatous meningitis: Usefulness of CSF biochemical markers

Cytologically negative carcinomatous meningitis: Usefulness of CSF biochemical markers
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DOI:
10.1212/wnl.50.4.1173
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发表时间:
1998-04-01
期刊:
影响因子:
9.9
通讯作者:
Chamberlain, MC
Chamberlain, MC
中科院分区:
医学1区
文献类型:
--
作者:
Chamberlain, MC

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18例(年龄28 - 62岁,中位58岁)临床确诊为癌性脑膜炎的患者(100%)和脑脊液细胞学阴性的神经放射学患者(39%)采用脑脊液生化标志物进行评估。只有4例(22%)患者脑脊液生化标志物证实了癌性脑膜炎的诊断。
Eighteen patients (age range, 28 to 62 years; median, 58) with carcinomatous meningitis defined clinically (100%) and neuroradiographically (39%) with negative CSF cytology were evaluated with CSF biochemical markers. In only four patients (22%), CSF biochemical markers corroborated a diagnosis of carcinomatous meningitis.