Prevalence of lower respiratory tract infections in hospitalized patients in the United Kingdom and Eire - results from the Second National Prevalence Survey

Prevalence of lower respiratory tract infections in hospitalized patients in the United Kingdom and Eire - results from the Second National Prevalence Survey
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DOI:
10.1053/jhin.2000.0775
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发表时间:
2000-09-01
影响因子:
6.9
通讯作者:
Emmerson, AM
Emmerson, AM
中科院分区:
医学3区
文献类型:
--
作者:
Kelsey, MC;Mitchell, CA;Emmerson, AM

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在1993年和1994年期间,医院感染学会对英国医院的病人进行了第二次全国感染率调查。医院获得性(HX)和社区获得性(CA)下呼吸道感染(LRTI)的患病率分别为2.4%和6.1%;这表明比第一次全国患病率研究报告的患病率有所增加。机械通气患者HA感染的患病率为18.6%。男性HA-LRTI(1.4,1.1-1.6)和CA-LRTI(1.2,1.1 - 1.3)的患病率、比值比(OR,95%CI)均高于女性。在HA-LRTI和CA-LRTI的情况下,年龄>75岁的患者的患病率增加(HA-LRTI 1.7,1.3-2.2; CA-LRTI 1.7,1.0-2.7)。多变量logistic回归分析结果显示,在使用鼻胃管(3.6,2.3-3.6)、机械通气(2.3-3.6)和呼吸机(2.3-3.6)的患者中,HA-LRTI的风险增加。创伤患者(2.2,1.5-3.0),慢性阻塞性气道疾病(COAD),(1.9,1.3-2.3)。气管切开术(1.9,1.3-2.7)、既往输血(1.5,1.2-1.8)、吸烟者(1.4,1.1-1.6)或全身皮质类固醇治疗(OK 1.3,1.1-1.6)。社区获得性LRTI与囊性纤维化(33.7,19.1-59.3)、HIV(9.8,6.5-14.8)、COAD(4.8,3.8-4.8)、全身皮质类固醇治疗(2.5,2.2-2.8)、气管切开术呈正相关。(1.8,1.1-2.9),男性(1.2,1.1-1.3)和吸烟(1.2,1.1-1.4)。(C)2000年,医院感染协会。
During 1993 and 1994, the Hospital infection Society; conducted its Second National Prevalence Survey of infections in patients in British hospitals. The prevalence rates for hospital-acquired (HX) and community-acquired (CA), lower respiratory tract infections (LRTIs) were 2.4% and 6.1%, respectively; this shows an increase over that reported in the First National Prevalence Study The prevalence rate of HA infections for ventilated patients was 18.6%. The prevalence was greater in males, odds ratio (OR, 95% CI) for HA-LRTIs (1.4, 1.1-1.6) and CA-LRTIs (1.2, 1.1-1.3) than in females. In the case of both HA-LRTIs and CA-LRTIs, there was an increase in prevalence in patients with age >75 years, (HA-LRTIs 1.7, 1.3-2.2; CA-LRTIs 1.7, 1.0-2.7). Results of multivariable logistic regression analysis showed an increased risk of HA-LRTIs in patients who had a nasogastric tube (3.6, 2.3-3.6), were ventilated (2.3. 1.6-3.2), trauma patients (2.2, 1.5-3.0), chronic obstructive airway disease (COAD), (1.9, 1.3-2.3). a tracheostomy (1.9, 1.3-2.7), prior blood transfusion (1.5, 1.2-1.8), smokers (1.4, 1.1-1.6) or on systemic corticosteroid therapy (OK 1.3, 1.1-1.6). Community-acquired LRTIs were positively associated with cystic fibrosis (33.7, 19.1-59.3), HIV (9.8, 6.5-14.8), COAD (4.8, 3.8-4.8), systemic corticosteroid therapy (2.5, 2.2-2.8), tracheostomy. (1.8, 1.1-2.9), males (1.2, 1.1-1.3) and smoking (1.2, 1.1-1.4). (C) 2000 The Hospital Infection Society.