Distribution of pyrethroid and DDT resistance and the L1014F kdr mutation in Anopheles gambiae s.l. from Burkina Faso (West Africa)
Distribution of pyrethroid and DDT resistance and the L1014F kdr mutation in Anopheles gambiae s.l. from Burkina Faso (West Africa)
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DOI：
10.1016/j.trstmh.2009.01.008
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发表时间：
2009-11-01
影响因子：
2.2
通讯作者：
Baldet, T.
中科院分区：
文献类型：
--
作者：
Dabire, K. R.;Diabate, A.;Baldet, T.
本文报道了2006年8 - 10月布基纳法索3个不同气候带21个地点冈比亚按蚊种群对拟除虫菊酯类杀虫剂和滴滴涕的抗性分布及L1014F低敲抗性突变情况。采用滴滴涕（4%）、氯菊酯（1%）和溴氰菊酯（0.05%）进行生物测定。冈比亚按蚊在苏丹地区对氯菊酯和滴滴涕均有抗性，但在中部和萨赫勒地区对氯菊酯敏感，在除奥罗达拉以外的所有地点对溴氰菊酯敏感，尽管一些种群的死亡率值接近抗性阈值。苏克拉尼亚地区人群的kdr频率在0.4 ~ 0.97之间，苏丹-萨赫勒地区和萨赫勒地区人群的kdr频率最高（0.047 ~ 0.54）。与上次调查结果比较。在2000年对冈比亚种群进行的调查中，kdr频率在S型中没有差异，但在M型中有所增加（0.6），并扩展到苏丹-萨赫勒地区。kdr的发生频率在安省也有所增加。Arabiensis居群（0.28），以前仅在单个标本中报道。这些结果对疟疾病媒控制具有实际意义。(C) 2009年皇家热带医学与卫生学会。Elsevier Ltd.出版。版权所有。
The study reports on the distribution of pyrethroid and DDT resistance and the L1014F knockdown resistance (kdr) mutation in Anopheles gambiae s.l. populations from 21 localities in three different climatic zones of Burkina Faso from August to October 2006. The susceptibitity of these populations was assessed by bioassay using DDT (4%), permethrin (1%) and deltamethrin (0.05%). Anopheles gambiae were resistant to both permethrin and DDT in the Sudanian regions but were susceptible in the central and sahelian areas and susceptible to deltamethrin at all sites except Orodara, although mortality values in some populations were close to the resistance threshold. The kdr frequency varied from 0.4 to 0.97 in populations from the Suclanian region and was tower in populations from the Sudano-sahelian and sahelian areas (0.047 to 0.54). Compared to the last survey of kdr in An. gambiae populations conducted in 2000, the kdr frequency did not differ in the S form but had increased in the M form (0.6), with an extended distribution into the Sudano-sahelian region. The frequency of kdr was also found to have increased in An. arabiensis populations (0.28), where it was formerly reported in only a single specimen. These results have practical significance for malaria vector control, programs. (C) 2009 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.