Studies of Pediatric Liver Transplantation: 2002 update. An overview of demographics, indications, timing, and immunosuppressive practices in pediatric liver transplantation in the United States and Canada
Studies of Pediatric Liver Transplantation: 2002 update. An overview of demographics, indications, timing, and immunosuppressive practices in pediatric liver transplantation in the United States and Canada
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DOI：
10.1111/j.1399-3046.2004.00153.x
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发表时间：
2004-06-01
影响因子：
1.3
通讯作者：
Lindblad, AS
中科院分区：
文献类型：
--
作者：
McDiarmid, SV;Anand, R;Lindblad, AS
儿童肝移植研究（SPLIT）始于1995年，目的是收集接受肝移植的儿童的综合数据。截至2002年5月31日，来自美国和加拿大38个参与中心的1761名儿童在SPLIT注册。本报告的重点是在SPLIT登记后接受肝移植的1187名儿童的人口统计学、初步诊断、移植的临床适应症和获得肝移植的概率。还提供了第一次接受肝移植的1092名儿童的人口统计信息。对于这个队列，我们还描述了移植时的免疫抑制实践，以及不同药物的使用如何随时间变化。
Studies of Pediatric Liver Transplantation (SPLIT) was initiated in 1995 for the purpose of collecting comprehensive data from children undergoing liver transplantation. As of May 31, 2002, 1761 children were registered in SPLIT from 38 participating centers in the United States and Canada. This report focuses on the demographics, primary diagnoses, clinical indications for transplant, and probability of obtaining liver transplantation for the 1187 children receiving a liver transplant after registration in SPLIT. Demographic information is also provided for the 1092 children who received their first ever liver transplantation. For this cohort, we also describe immunosuppressive practices at the time of transplant, and how the use of different medications changes with time.