PLACENTAL BED BIOPSIES IN PLACENTAL ABRUPTION
PLACENTAL BED BIOPSIES IN PLACENTAL ABRUPTION
复制标题
DOI：
10.1111/j.1471-0528.1992.tb13848.x
复制
发表时间：
1992-08-01
期刊：
影响因子：
--
通讯作者：
TILTMAN, AJ
中科院分区：
文献类型：
--
作者：
DOMMISSE, J;TILTMAN, AJ
目的探讨子宫胎盘血管结构变化与胎盘早剥的关系。设计前瞻性描述性研究。对18例剖宫产重度胎盘早剥患者进行剖宫产胎盘床活检。结果6例子宫肌层不含滋养细胞，不能代表胎盘床。在12个有代表性的标本中，有7个显示子宫胎盘动脉没有生理性转化(其中4个来自高血压患者)。4例活检显示子宫肌层深层有异常血管结构。结论与胎盘早剥相关的血管畸形可能是滋养层侵袭的结果，可能是血管破裂的部位。还需要进一步的描述性研究和比较研究。
Objective To investigate structural changes in the uteroplacental blood vessels in association with placental abruption.Design Prospective descriptive study.Subjects 18 women with clinical evidence of severe placental abruption delivered by caesarean section.Interventions Placental bed biopsies were obtained at caesarean section and studied histologically.Results Six specimens did not include trophoblast in the myometrium and were therefore not representative of the placental bed. Of the 12 representative specimens, seven demonstrated absence of physiological transformation of the utero-placental arteries (four of these were from hypertensive patients). Four biopsies showed abnormal vascular structures deep in the myometrium. One of these abnormal vessels included a fresh plug and extensive surrounding intramyometrial haemorrhage.Conclusions Vascular malformations in association with placental abruption may be the result of trophoblastic invasion and could be the site of vessel rupture. Further descriptive and comparative studies are needed.