Does Physiological Hyperarousal Enhance Error Rates among Insomnia Sufferers?
Does Physiological Hyperarousal Enhance Error Rates among Insomnia Sufferers?
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DOI：
10.5665/sleep.2882
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发表时间：
2013-08-01
期刊：
影响因子：
5.6
通讯作者：
Krystal, Andrew D.
中科院分区：
文献类型：
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作者：
Edinger, Jack D.;Means, Melanie K.;Krystal, Andrew D.
目的：研究失眠症患者生理性过度觉醒与反应时间任务的反应准确性之间的关系。设计和设置：本研究在附属退伍军人管理局（VA）和学术医疗中心进行，采用配对组，横断面研究设计。参与者：八十九人（48名女性）原发性失眠，PI（男性-年龄= 49.8 +/- 17.2岁）和95名个体（48名妇女），他们是经过良好筛选的正常睡眠者，NS（M-年龄= 46.9 +/-17.0岁）。方法和测量：参与者经历了3个晚上的多导睡眠图，然后是用四次试验的多次睡眠潜伏期测试（MPEST）进行的白天测试。在每次小睡之前，他们评估自己的困倦程度，并完成计算机管理的反应时间任务。每个参与者在测试试验中做出的正确和错误回答的平均数作为依赖性测量。PI组和NS组分别被细分为警戒组（例如，平均发作潜伏期> 8分钟）和嗜睡（例如，平均起始潜伏期
Objective: To examine the association between physiological hyperarousal and response accuracy on reaction time tasks among individuals with insomnia.Design and Setting: This study was conducted at affiliated Veterans Administration (VA) and academic medical centers using a matched-group, cross-sectional research design.Participants: Eighty-nine individuals (48 women) with primary insomnia, PI (M-Age = 49.8 +/- 17.2 y) and 95 individuals (48 women) who were well-screened normal sleepers, NS (M-Age = 46.9 +/- 17.0 y).Methods and Measures: Participants underwent 3 nights of polysomnography followed by daytime testing with a four-trial Multiple Sleep Latency Test (MSLT). Before each MSLT nap, they rated their sleepiness and completed computer-administered reaction time tasks. The mean number of correct and error responses made by each participant across testing trials served as dependent measures. The PI and NS groups were each subdivided into alert (e.g., MSLT mean onset latency > 8 min) and sleepy (e.g., MSLT mean onset latency