Association between sucrose intake and cancer: a review of the evidence
Association between sucrose intake and cancer: a review of the evidence
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DOI：
10.3305/nh.2013.28.sup4.6802
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发表时间：
2013-07-01
期刊：
影响因子：
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通讯作者：
Pérez Rodrigo, Carmen
中科院分区：
文献类型：
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作者：
Aranceta Bartrina, Javier;Pérez Rodrigo, Carmen
目的：本综述的目的是总结现有的关于糖摄入量，特别是蔗糖摄入量与不同类型癌症风险之间关系的证据。方法：对2007年1月1日至2012年12月31日之后发表的关于糖摄入量（特别是蔗糖）结果：单糖和二糖的摄入量与不同类型的癌症的关联的证据是不够的，或者有证据表明缺乏关联。只有可能的证据表明单糖（果糖和葡萄糖）的摄入量与胰腺癌之间存在正相关关系。关于单糖摄入量与肥胖之间的联系以及蔗糖或添加糖的摄入量与成人和儿童肥胖风险之间的联系的证据不足。有可能的证据表明，血糖指数（GI）和结直肠癌之间的正相关，并有GI和子宫内膜癌，乳腺癌和胰腺癌的风险之间没有关联。结论：需要更多的研究。特别需要队列研究，随机干预试验也是可取的，尽管这在这一领域很困难。
Objectives: The aim of this review is to summarize the evidence available about the association between sugar consumption, especially sucrose, and the risk of different types of cancer.Methods: A systematic review was conducted of key reports, systematic reviews, meta-analysis as well as big prospective studies published after 2007 January 1 thru 2012 December 31 about the association between sugar consumption, especially sucrose, and the risk of cancer.Results: Evidence of the association of the intake of mono- and disaccharides with different types of cancer is insufficient or there is evidence of lack of association. There is only possible evidence of a positive relation between the intake of monosaccharides (fructose and glucose) and pancreatic cancer. Evidence about the association between monosaccharides' intake and obesity is insufficient, as well as between the intake of sucrose or added sugars and the risk of obesity in adults and children. There is possible evidence of a positive association between glycemic index (GI) and colorectal cancer and that there is no association between GI and the risk of endometrial cancer, breast cancer and pancreas cancer.Conclusion: More research is needed. Cohort studies are especially required and randomized intervention trials would be desirable, although these are difficult in this field.