A functional magnetic resonance imaging study of mental subtraction in human subjects

A functional magnetic resonance imaging study of mental subtraction in human subjects
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DOI:
10.1016/s0304-3940(99)00641-2
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发表时间:
1999-10-08
影响因子:
2.5
通讯作者:
Allard, M
Allard, M
中科院分区:
医学4区
文献类型:
--
作者:
Burbaud, P;Camus, O;Allard, M

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通过功能磁共振成像研究了参与精确计算过程(心算减法)的神经元网络。使用了两项需要秘密产生数字的任务:(1)计算; (2)无需计算。在第一个任务中,在左背外侧前额叶和前运动皮质、布罗卡区和双侧下顶叶皮质中观察到激活。在第二项任务中,主要在布罗卡区观察到激活,在左前额叶和前运动皮质中观察到较小程度的激活。两种情况下数据的统计比较表明,心理减法的过程是由分布式系统介导的,该系统主要包括左背外侧前额叶皮层和双边下顶叶皮层。 (C) 1999 Elsevier Science Ireland Ltd. 保留所有权利。
The neuronal network involved in a precise type of calculation procedure, mental subtraction, was investigated by means of functional magnetic resonance imaging. Two tasks were used requiring covert production of numbers: (1) with calculation; (2) without calculation. During the first task, activation was observed in the left dorsolateral prefrontal and premotor cortices, in Broca's area and bilaterally in the inferior parietal cortex. During the second task, activation was mainly observed in Broca's area and to a less extent in the left prefrontal and premotor cortices. Statistical comparison of data in the two situations revealed that the procedure of mental subtraction is mediated by a distributed system which includes predominantly the left dorsolateral prefrontal cortex and the inferior parietal cortex bilaterally. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.