Peptide-membrane interactions and biotechnology; enabling next-generation synthetic biology: general discussion.
Peptide-membrane interactions and biotechnology; enabling next-generation synthetic biology: general discussion.
复制标题
肽膜相互作用和生物技术；
DOI：
10.1039/d1fd90068d
复制
发表时间：
2021
影响因子：
3.4
通讯作者：
Aguilar M
中科院分区：
文献类型：
--
作者：
Aguilar M
罗纳德·J·克拉克对米贝尔阿吉拉尔的论文展开了一般性的讨论：关于脂质在细菌膜上的分布，有什么已知的吗？即它是不对称的吗？当磷脂酰甘油含量在固定相中上升时，是在两个莱亚膜中还是仅在膜的一侧？Mibel阿吉拉尔回答说：关于细菌细胞膜的不对称性，人们所知的比哺乳动物细胞膜少，但有证据表明，脂质的动态管理系统正在出现。Bogdanov等人1最近的一项研究表明，PE水平在细胞质和周质层中不同，并且PE水平响应于不同的环境因素而调节。
Ronald J. Clarke opened a general discussion of the paper by Mibel Aguilar: Is there anything known about the distribution of lipids across the bacterial membrane, ie is it asymmetric? When the phosphatidylglycerol content goes up in the stationary phase, is it in both lea ets or only on one side of the membrane?Mibel Aguilar responded: There is less known about the asymmetry of bacterial membranes than mammalian membranes but evidence is emerging of a dynamic system of lipid curation. A recent study by Bogdanov et al. 1 showed that PE levels are different in the cytoplasmic and periplasmic layers, and that the PE levels are modulated in response to different environmental factors.