Papanicolaou Screening Behavior in Mothers and Human Papillomavirus Vaccine Uptake in Adolescent Girls
Papanicolaou Screening Behavior in Mothers and Human Papillomavirus Vaccine Uptake in Adolescent Girls
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DOI：
10.2105/ajph.2008.147876
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发表时间：
2009-06-01
影响因子：
12.7
通讯作者：
Jacobsen, Steven J.
中科院分区：
文献类型：
--
作者：
Chao, Chun;Slezak, Jeff M.;Jacobsen, Steven J.
目标.我们调查了母亲对预防的态度，如寻求巴氏（Pap）试验和感染性传播感染的历史所示，是否影响了她们青春期女儿对人乳头瘤病毒（HPV）疫苗的接种。我们将9至17岁的女孩的电子健康记录与他们的母亲在南加州凯撒永久（n=148350母女对）。在女儿和母亲的匹配完成后，个人身份信息被从数据集中删除。我们使用逻辑回归模型来检测母亲的巴氏试验史和异常结果、生殖器或肛门疣和其他性传播感染与女儿的HPV疫苗启动和3剂方案完成之间的关联。母亲的检测史与女儿接种疫苗的可能性在种族和社区社会经济阶层中相关（总体比值比[OR]=1.47; 95%置信区间[CI]=1.43，1.52）。母亲的性传播感染史与女儿的疫苗接种仅适度相关。母亲的检测史与女儿的治疗方案完成呈正相关（总OR=1.42，95%CI =1.31，1.54）。母亲对预防的态度可能会影响青春期女孩的HPV疫苗接种。HPV疫苗接种计划应考虑针对母亲的影响，并通过进一步的研究进行调查。（美国公共卫生杂志）2009;99：1137-1142. doi：10.2105/AJPH.2008.147876）
Objectives. We investigated whether maternal attitude toward prevention, as indicated by history of seeking Papanicolaou (Pap) tests and contracting sexually transmitted infections, influenced human papillomavirus (HPV) vaccine uptake among their adolescent daughters.Methods. We linked the electronic health records of girls aged 9 to 17 years with their mothers at Kaiser Permanente Southern California (n=148350 mother-daughter pairs). Personal identifying information was removed from the data set after the matching of daughters and mothers was completed. We used logistic regression models to detect associations between mothers' history of Pap tests and abnormal results, genital or anal warts, and other sexually transmitted infections and daughters' HPV vaccine initiation and 3-dose regimen completion.Results. Mothers' testing history was associated with daughters' likelihood for vaccination across ethnic and neighborhood socioeconomic strata (overall odds ratio [OR]=1.47; 95% confidence interval [CI]=1.43, 1.52). Mothers' history of sexually transmitted infections was only modestly associated with daughters' vaccination. Mothers' testing history was positively associated with daughters' regimen completion (overall OR=1.42; 95% CI=1.31, 1.54).Conclusions. Mothers' attitude toward prevention may influence HPV vaccine uptake among adolescent girls. The impacts of targeting mothers should be considered by HPV vaccination programs and investigated by further research. L (Am J Public Health. 2009;99:1137-1142. doi:10.2105/AJPH.2008.147876)