PLATELET GLYCINE, GLUTAMATE AND ASPARTATE IN PRIMARY HEADACHE

PLATELET GLYCINE, GLUTAMATE AND ASPARTATE IN PRIMARY HEADACHE
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DOI:
10.1046/j.1468-2982.1991.1104197.x
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发表时间:
1991-09-01
期刊:
影响因子:
4.9
通讯作者:
WELCH, KMA
WELCH, KMA
中科院分区:
医学2区
文献类型:
--
作者:
DANDREA, G;CANANZI, AR;WELCH, KMA

文献摘要

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对有先兆偏头痛、无先兆偏头痛、紧张性头痛和丛集性头痛患者血小板谷氨酸、天冬氨酸和甘氨酸水平进行了测定。与正常受试者和其他头痛组相比,在有先兆的偏头痛患者中发现了高水平的这些氨基酸。在头痛期间,有先兆的偏头痛患者的谷氨酸水平进一步升高。这些发现可能与先兆偏头痛的神经症状有关。
Platelet levels of glutamic and aspartic acid and glycine were measured in patients with migraine with aura, migraine without aura, tension headache and cluster headache. High levels of these amino acids were found in patients with migraine with aura compared to normal subjects and other headache groups. During headache, glutamate levels further increased in migraine with aura patients. These findings may have relevance to the neurological symptoms of migraine with aura.