Design, optimization, and selective laser melting of vin tiles cellular structure-based hip implant
Design, optimization, and selective laser melting of vin tiles cellular structure-based hip implant
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DOI：
10.1007/s00170-020-06323-5
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发表时间：
2021-01-06
影响因子：
3.4
通讯作者：
Jeng, Jeng-Ywan
中科院分区：
文献类型：
--
作者：
Abate, Kalayu Mekonen;Nazir, Aamer;Jeng, Jeng-Ywan
具有高度可控微结构的细胞生物材料是用于医学骨科应用的有利材料，无论是作为支架还是植入物，由于它们能够促进更好的骨整合和细胞增殖。这项工作的重点是髋关节植入物的设计和优化，通过引入蜂窝结构到一个固体植入物，以允许骨组织向内生长，并减少应力遮挡。多孔髋关节植入物与具有不同支柱厚度和单元尺寸的vintiles网格拓扑结构结合，以实现骨长入和生物力学模拟强度的要求。采用Ti6 Al 4V材料，通过选择性激光熔化（SLM）制造了具有不同晶胞尺寸和孔隙率的所有四种优化的蜂窝状髋关节植入物。为了预测髋关节多孔植入物的力学性能，采用有限元分析方法，并采用优化方法来提高髋关节多孔植入物的力学性能。为了评价髋关节多孔植入物的刚度降低，根据ISO 7206-4（2010）在静态载荷条件下进行了实验测试。实验和模拟的力-位移结果表明，优化后的蜂窝状髋关节植入物的刚度比其固体对应物低62%。此外，蜂窝状髋关节植入物的重量比实心植入物轻50%。最后，本研究的结果表明，孔隙率为56%和58%的细胞植入物具有用于骨科和假体应用以改善骨整合的潜力。
Cellular biomaterials with highly controlled microstructures are auspicious materials for medical orthopedics applications either as scaffold or implants due to their capability of encouraging better osseointegration and cell proliferation. This work focuses on the design and optimization of the hip implant by introducing a cellular structure into a solid implant to allow bone tissue ingrowth and reduce stress shielding. The cellular hip implant is incorporated with vintiles lattice topologies having different strut thickness and unit cell sizes to achieve the requirements of bone ingrowth and biomechanical mimic strength. All four optimized cellular hip implants with different unit cell size and porosity were manufactured via selective laser melting (SLM) using the Ti6Al4V material. To predict the mechanical property of hip cellular implant, finite element analysis (FEA) was employed and optimization methods were used for improving the mechanical performance of the hip cellular implant. To evaluate the reduction in stiffness of hip cellular implants, experimental tests were performed based on ISO 7206-4(2010) under static loading conditions. The experimental and simulation force-displacement results show that the optimized cellular hip implant has 62% lower stiffness than its solid counterpart. Moreover, the cellular hip implant was 50% lower in weight than the solid implant. Finally, the result of this study shows that the cellular implants with porosity of 56% and 58% have the potential to be used in orthopedic and prosthetic applications to improve osseointegration.