ECHOTOMOGRAPHIC AND SEROLOGICAL POPULATION-BASED STUDY OF HYDATIDOSIS IN CENTRAL TUNISIA
ECHOTOMOGRAPHIC AND SEROLOGICAL POPULATION-BASED STUDY OF HYDATIDOSIS IN CENTRAL TUNISIA
复制标题
DOI：
10.1016/0001-706x(91)90062-o
复制
发表时间：
1991-06-01
期刊：
影响因子：
2.7
通讯作者：
JEMMALI, M
中科院分区：
文献类型：
--
作者：
BCHIR, A;LAROUZE, B;JEMMALI, M
在突尼斯中部的一个高风险社区开展了一项基于人群的包虫病超声断层扫描（ECT）和血清学调查。1434名5岁以上的受试者（该年龄段人口的93.3%）接受了腹部超声断层扫描（ECT）和血清学检测（酶联免疫吸附试验，并通过对流免疫电泳进行确认）。ECT患病率为3.5%，且随年龄增长而上升，在39岁以上年龄组达到7.7%。大多数受试者（96.0%）有肝囊肿。血清学患病率为2.9%。ECT和血清学结果之间有很强的一致性（卡帕检验 = 0.449）。以ECT为参照，血清学的相对特异性和敏感性分别为99.3和62.0。大多数ECT阳性而血清学阴性的受试者有钙化囊肿。这些结果证实了突尼斯中部存在包虫病的高度流行区，表明在人群层面血清学和ECT结果有良好的一致性，并证明了ECT作为一种筛查技术具有很高的可行性。
A population-based echotomographic (ECT) and serological survey of hydatidosis was carried out in a high risk community located in Central Tunisia. 1434 subjects over 5 years of age (93.3% of the population in this age range) underwent an abdominal echotomography (ECT) and a serological test (ELISA with confirmation by counterelectrophoresis). The ECT prevalence rate was 3.5% and increased with age reaching 7.7% in the over 39 years age group. Most subjects (96.0%) had liver cyst(s). The serological prevalence rate was 2.9%. A strong agreement was found between ECT and serological results (Kappa test = 0.449). Taking ECT as a reference, the relative specificity and sensitivity of serology were 99.3 and 62.0 respectively. Most ECT positive seronegative subjects had calcified cysts. These results confirm the presence of highly endemic foci of hydatidosis in Central Tunisia, show a good agreement between serological and ECT results at a population level and demonstrate the high feasibility of ECT as a screening technique.