Pregnancy complications and birth outcomes in obese and normal-weight women: Effects of gestational weight change
Pregnancy complications and birth outcomes in obese and normal-weight women: Effects of gestational weight change
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DOI：
10.1016/0029-7844(95)00446-7
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发表时间：
1996-03-01
影响因子：
7.2
通讯作者：
Himes, JH
中科院分区：
文献类型：
--
作者：
Edwards, LE;Hellerstedt, WL;Himes, JH
目的：比较肥胖和正常体重妇女的妊娠过程和结局及其与妊娠期体重变化的关系。方法：对683例肥胖和660例正常体重妇女分娩单胎活产新生儿进行回顾性研究，采用多因素logistic回归分析描述体重变化与妊娠过程和结局的关系。与正常体重的女性相比，肥胖女性在怀孕期间平均少增加5公斤（11磅），更有可能减轻或不增加体重（11%对不到1%）。肥胖妇女明显更容易发生妊娠并发症，但并发症的发生率与体重变化无关。与体重增加7-11.5公斤的肥胖女性相比，（15-25磅），体重减轻或没有增加的肥胖妇女分娩3000 g以下或小于胎龄儿的风险更高，体重增加超过16 kg（35磅）的妇女分娩4000 g或更重婴儿的风险是其两倍。在肥胖或正常体重的妇女中，孕激素体重变化与妊娠并发症无关。为了优化胎儿生长，肥胖妇女体重增加7-11.5公斤（15-25磅），正常体重妇女体重增加11.5-16公斤（25-35磅）似乎是合适的。
Objective: To compare the pregnancy course and outcomes in obese and normal-weight women and their associations with gestational weight change.Methods: Multivariate logistic regression described the relation of weight change to pregnancy course and outcomes in a retrospective study of 683 obese and 660 normal-weight women who delivered singleton living neonates.Results: Compared with normal-weight women, obese women gained an average of 5 kg (11 lb) less during pregnancy and were more likely to lose or gain no weight (11% versus less than 1%). Obese women were significantly more likely to have pregnancy complications, but the incidence of complications was not associated with weight change. Compared with obese women who gained 7-11.5 kg (15-25 lb), obese women who lost or gained no weight were at higher risk for delivery of infants under 3000 g or small for gestational age infants, and those who gained more than 16 kg (35 lb) were at twice the risk for delivery of infants who were 4000 g or heavier.Conclusion: Gestational weight change was not associated with pregnancy complications in obese or normal-weight women. To optimize fetal growth, weight gains of 7-11.5 kg (15-25 lb) for obese women and 11.5-16 kg (25-35 lb) for normal-weight women appear to be appropriate.